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Multiple sequence alignment with the Clustal series of programs:(多序列比对的Clustal系列项目).pdf,Nucleic Acids Research, 2003, Vol. 31, No. 13 3497–3500 DOI: 10.1093/nar/gkg500 Multiple sequence alignment with the Clustal series of programs 1 1 Ramu
Multiple sequence alignment is an important tool to represent similarities among biological sequences and it allows obtaining relevant information such as evolutionary history, among others. Due to its importance, several methods have been proposed to the problem. However, the inherent complexity of the...
MOTIVATION: A tool that simultaneously aligns multiple protein sequences, automatically utilizes information about protein domains, and has a good compromise between speed and accuracy will have practical advantages over current tools. RESULTS: We describe COBALT, a constraint based alignment tool that im...
A candidate set of sequences was identified using BLASTp v.2.6.062using the protein sequence for KaiB fromS. elongatus(NCBI:WP_011242647.1) as a query. The query was run against the NCBI non-redundant protein database with the exclusion of models or uncultured/environmental sample sequences....
来自 NCBI 喜欢 0 阅读量: 47 作者:PT Minh,CB Do,RC Edgar,B Serafim 摘要: Multiple sequence alignments are the usual starting point for analyses of protein structure and evolution. For proteins with repeated, shuffled and missing domains, however, traditional multiple sequence alignment algorithms ...
(MUSCLE) Consistency (ProbCons) Structure-based (Expresso) Conclusions: benchmarking studies [2] Hidden Markov models (HMMs), Pfam and CDD [3] MEGA to make a multiple sequence alignment [4] Multiple alignment of genomic DNA Multiple sequence alignment: methods How do we know which program to...
Multiple comparison or alignmentof protein sequences has become a fundamental tool in many different domains in modern molecular biology, from evolutionary studies to prediction of 2D/3D structure, molecular function and inter-molecular interactions etc. By placing the sequence in the framework of the...
MUSCLE: a multiple sequence alignment method with reduced time and space complexity BMC Bioinformatics 2004, 5:113 doi:10.1186/1471-2105-5-113 Robert C Edgar (bob@drive5.com) ISSN 1471-2105 Article type Software Submission date 25 Mar 2004 Acceptance date 19 Aug 2004 Publication date 19 Aug ...
Input for the algorithm is a multiple sequence alignment in a standard format. The NCBI Conserved Domain Database (CDD) is used for finding conserved domains along the alignment. The visualization quickly identifies conserved domains, and allows both macro (sequence-long) and micro (small amino-...