Multiple sclerosis (MS) is a neurodegenerative disease in which axonal loss is the major cause of irreversible neurological disability. Neurological deficits in MS patients are related to inflammatory demyelination and axonal degeneration. Axonal transection occurs at sites of inflammation and begins at ...
Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the human central nervous system. The clinical disease course is variable, usually starts with reversible episodes of neurological disability in the third or fourth decade of life, and transforms into a disease of continuous ...
Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most prevalent in Northern Europe. Although it is known that inherited risk for MS is located within or in close proximity to immune-related genes, it is unknown when, where and how this genetic risk originated...
Multiple Sclerosis: An Immune or Neurodegenerative Disorder? - Annual Review of Neuroscience, 31(1):247 Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the human central nervous system. The clinical disease course is variable, usually starts with reversible episodes of ...
Multiple sclerosis (MS) is a neurodegenerative disorder caused by the immune system mistakenly attacking the myelin sheath, a protective coating around nerve fibers. This results in inflammation, which further damages the myelin sheath, as well as the nerve cells themselves and the cells that ...
1Multiple sclerosis Multiple sclerosisis a chronic inflammatory andneurodegenerative diseaseof thecentral nervous system(CNS), and it is one of the most common neurological (non-traumatic) cause of disability in young adults (Rahmanzadeh et al., 2019;Society, 2019). This disease leads to a progre...
Multiple sclerosis (MS) is the most common chronic inflammatory, demyelinating and neurodegenerative disease of the central nervous system in young adults. This disorder is a heterogeneous, multifactorial, immune-mediated disease that is influenced by both genetic and environmental factors. In most patien...
Neurodegenerative diseases such as Alzheimer's Disease, multiple sclerosis, Huntington's Disease, or Parkinson's Disease, AIDS related dementia, Amyotrophic Lateral Sclerosis; use of compounds derived from a 4,4,8-trimethyl-17-furanylsteroid skeleton, tetranortriterpenoids...
Multiple sclerosis is an autoimmune demyelinating disorder of the CNS, characterized by inflammatory lesions and an underlying neurodegenerative process, w... W Maureen,LG Carlos,P Hye-Jin,... - 《Brain》 被引量: 0发表: 2020年 Aberrant DNA methylation profile exacerbates inflammation and neurodegene...
Chapter 16 – Mechanisms of Blood–Brain Barrier Disintegration in the Pathophysiology of Multiple SclerosisMultiple sclerosis (MS) is a demyelinating and neurodegenerative disease of the human brain, optic nerves, and spinal cord, which... EV Stevenson,JS Alexander,JW Yun,... - 《Multiple Sclerosi...