By using density-transfer and marker-rescue techniques, we have been able to determine that: (1) SPOT has at least two origins of replication; (2) one of these origins is located about 8% from the right-hand end of the genetic map (in or near cistron 32) and replication proceeds ...
Single-stranded (ss) DNA viruses are a major component of the earth virome. In particular, the circular, Rep-encoding ssDNA (CRESS-DNA) viruses show high diversity and abundance in various habitats. By combining sequence similarity network and phylogenetic analyses of the replication proteins (Rep...
The HeLa pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication. Mol Cell Biol. 1992;12(3):1257–65. CAS PubMed PubMed Central Google Scholar Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, et al. ...
Multiple mechanisms involving geminin inhibition of CDT1 function, CDT1 phosphorylation, and CDK inhibition of pre-RC assembly all contribute to prevention of re-licensing of origins of DNA replication during S and G2 phases (Lygerou and Nurse, 2000; Wohlschlegel et al., 2000; Zhou et al.,...
The HeLa pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication. Mol Cell Biol. 1992;12(3):1257–65. CAS PubMed PubMed Central Google Scholar Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, et al. ...
Eukaryotes have many linear chromosomes and they possess many origins of replication. Across the human genome, 100000 origins of replication sites are...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
The origins of and reasons for this geographical variation are poorly understood, yet such biases may hold important clues as to why the prevalence of autoimmune diseases, including MS, has continued to rise during the past 50 years. Although still elusive, MS aetiology is thought to involve ...
William Martin, University of Duesseldorf This is an interesting, worthwhile, and scholarly paper. I think it should be published, but I have a request. Can the authors suggest a convention for circular chromosomes and plasmids based on origins of replication (oris)?
(142.81 cases per 100,000 people); Northern Europeans are particularly susceptible to developing the disease3. The origins of and reasons for this geographical variation are poorly understood, yet such biases may hold important clues as to why the prevalence of autoimmune diseases, including MS, ...
The term "nucleic acid construct," or the abbreviated form "construct," as used herein, and throughout the specification and claims, refers to a recombinant nucleic acid molecule which can include expression cassettes, origins of DNA replication, procaryotic and eucaryotic genes from various ...