Background: There is limited published information regarding feline multiple myeloma. Diagnostic criteria are derived from canine studies and to our knowledge, have not been critically reviewed for cats. Objective: To evaluate the clinical and laboratory findings in cats with multiple myeloma and...
Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. [1] First described in 1848, MM is part of...
tumor heterogeneity, tumor microenvironment, therapeutic resistance in MM, which offers a profound opportunity to improve the diagnosis and identify biomarkers for precision medicine of MM. SCS: single-cell sequencing; MM: multiple myeloma; MGUS: monoclonal...
an experimental drug, for the treatment of the heterogeneous cancer disease multiple myeloma in patients who had relapsed on standard therapies. The findings are published in theAmerican Journal of Hematologyand provide new hope for the treatment of multiple myeloma. ...
multiple myeloma By The ASCO Post Staff/2024 ASCO Annual Meeting Amrita Y. Krishnan, MD, and Paula Rodríguez-Otero, MD, PhD, on Multiple Myeloma: Findings From the PERSEUS Trial on a Regimen for Transplant-Eligible Patients Amrita Y. Krishnan, MD, of the City of Hope Cancer Center, and ...
Objective: To evaluate the clinical and laboratory findings in cats with multiple myeloma and appraise diagnostic criteria. Methods: Retrospective evaluation of medical records was performed. Inclusion required an antemortem diagnosis of multiple myeloma using 2 of 4 criteria: 1) ≥20% plasma cells ...
Roundtable Roundup: Choosing a Bispecific Antibody for R/R Multiple Myeloma ByTargeted Oncology Staff December 23rd 2024 Talquetamab Tolerability and Dose Interruption Considered in R/R MM ByTargeted Oncology Staff December 18th 2024 Fellow's Perspective: Impact of Quadruplet and MRD in Newly Diagnos...
Substantial improvements in survival have been seen in multiple myeloma (MM) over recent years, associated with the introduction and widespread use of multiple novel agents and regimens, as well as the emerging treatment paradigm of continuous or long-term therapy. However, these therapies and ...
Serum free light chain measurement:This test measures the amount of light chain, a type of myeloma protein, in the blood. Prognostic indicators:Various blood tests are used to predict the outcome (prognosis) for an individual. Some of these are simple tests done in every laboratory; others are...
Multiple myeloma (MM) is an incurable haematological malignancy, caused by the uncontrolled proliferation of plasma cells within the bone marrow (BM). Obesity is a known risk factor for MM, however, few studies have investigated the potential of dietary