Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. [1] First described in 1848, MM is part of...
Multiple myeloma (MM) or plasma cell myeloma, is a haematological disease representing 1-2% of all cancers and about 15% of haematological malignancies. The classic form of MM is characterized by generalized neoplastic changes in the bones accompanied by kidney damage, impaired haematopoiesis and ...
Multiple myeloma (MM) is a malignant plasma cell disease in which tumor cells originate from plasma cells in the bone marrow, and plasma cells are cells that develop to the final stage of function of B lymphocytes. Therefore, multiple myeloma can be classified as B lymphocyte lymphoma. The ...
Multiple myeloma is cancer of the bone marrow caused by the uncontrolled growth of plasma cells. These cells are one type of white blood cells. Normally, they make antibodies called immunoglobulins to fight infections. In multiple myeloma, cancerous plasma cells multiply rapidly in the bone marrow...
Serum free light chain measurement:This test measures the amount of light chain, a type of myeloma protein, in the blood. Prognostic indicators:Various blood tests are used to predict the outcome (prognosis) for an individual. Some of these are simple tests done in every laboratory; others are...
MultipleMyeloma(MM) 实验内容: •掌握MM的诊断思路及骨髓象的主要特点 •了解IM的血象特征 A58-year-oldmalegavechiefcomplaintof increasingfatigueandpaininhislowerback whenhewalked. LaboratoryFindings: Hb85g/L;RBC3.2×10 12 /L;WBC5.6×10 9 /L; PLT300×10 9 /L;ESR50mm/h X-rayindicatedbonele...
A diagnosis of multiple myeloma (MM) is difficult to make on the basis of any single laboratory test result. Accurate diagnosis of MM generally results from a number of costly and invasive laboratory tests and medical procedures. The aim of this work is to find a new, highly specific and ...
Objective To explore the value of laboratory tests for the diagnosis of multiple myeloma. Methods The clinical data of bone marrow cell morphology, serum protein electrophoresis, immunoelectrophoresis and immunoglobulin in one patient with multiple myeloma were reviewed and analyzed. Results Immunoglobulin ...
Multiple Myeloma (Symptomatic), Additional Treatment, Refractory disease and lack of treatment options, modiied: Continue palliative care; consider re-evaluation of goals of care and hospice initiation • Footnote cc added: Folllow up with the tests listed on MYEL-4 under follow-up/surveillance...
The pathogenesis of multiple myeloma involves complex genetic and epigenetic events. This study aimed to investigate the role and clinical relevance of the long non-coding RNA (lncRNA), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in m