We evaluated MTHFR genotypes and breast cancer survival in a cohort of 1067 Chinese women diagnosed with breast cancer between 1996 and 1998 who received surgery and chemotherapy. Life table method was used to calculate 5-year survival rates. Cox proportional hazards models were used to estimate ...
[3]. Sohn, K.J., et al., Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. J Natl Cancer Inst, 20 [4]. Etienne, M.C., et al., Methylenetetrahydrofolate reductase gene polymorphisms ...
MTHFR Polymorphisms, Dietary Folate Intake, and Breast Cancer Risk: Results from the Shanghai Breast Cancer Study 喜欢 0 阅读量: 6 作者: M.,J.,Shrubsole 摘要: Video cameras are at an eternal disadvantage to the human eye and brain. No lens is as sophisticated as the eye, no set of...
BMC Cancer (2020) 20:234 https://doi.org/10.1186/s12885-020-06749-w RESEARCH ARTICLE Open Access MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: a case- control study in a population from North Sardinia Matteo Floris1*†, Daria Sanna1†, Paolo Castiglia2, Carlo Putzu3...
MTHFR A1298C polymorphism might contribute to an increased risk of breast cancer and/or ovarian cancer susceptibility. In addition, MTHFR A1298C polymorphism had a significant association with breast cancer in Caucasians. 展开 关键词: Breast cancer Ovarian cancer MTHFR A1298C Polymorphism Meta-...
青岛大学硕士学位论文CHD5基因甲基化及叶酸代谢相关基因MTHFR、MS多态与乳腺癌发病的关系姓名:***请学位级别:硕士专业:生物化学与分子生物学指导教师:**20100604捅斐背景与目的DNA甲基化是一种影响基因表达的机制,并与肿瘤发生有着密切的联系,其状态的改变是致癌作用的一个关键因素,也是肿瘤抑癌基因的失活方式之一。...
OBJECTIVE: we conducted a case-control study to investigate the association between dietary folate, vitamin B6 and vitamin B12 intake, MTHFR and MTR genotype, and breast cancer risk. METHODS: Genotyping for MTHFR C677T and A1298C and MTR A2756G polymorphisms were performed using polymerase chain...
表1云南籍正常人群和乳腺癌人群血清叶酸浓度比较3hb.1TocomparewithnormalpopulationandthebreastcancertlleSer.umfolatelevelsinYunnanprovince95名乳腺癌患者中血清维生素B:浓度为(855.134-470.30)pg/ml,90名健康体检者维生素B。:浓度为(358.24±134.56)pg/ml,二者之间维生素B:浓度的差异有统计学意义(P<0.05)(表2)。
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MTHFR基因 C667T位点多态性与亚洲人群乳腺癌易感性的 Meta分析张之涛 1 ,杨仲俊 1 ,王晓琼 2 ,闫鹏1AssociationbetweenMTHFRC667TpolymorphismandthesusceptibilityofbreastcancerinAsianpopulation:AMeta-analysisZhangZhitao1,YangZhongjun1,WangXiaoqiong2,YanPeng11DepartmentofOncologySurgery;2GalactophoreDepartment,Zhangye...