Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis. Breast Can- cer Res Treat. 2008; 107: 459-460. PMID: 17453338Macis D, Maisonneuve P, Johansson H, Bonanni B, Botteri E, Iodice S, Santillo B, Penco S, ...
We evaluated MTHFR genotypes and breast cancer survival in a cohort of 1067 Chinese women diagnosed with breast cancer between 1996 and 1998 who received surgery and chemotherapy. Life table method was used to calculate 5-year survival rates. Cox proportional hazards models were used to estimate ...
BMC Cancer (2020) 20:234 https://doi.org/10.1186/s12885-020-06749-w RESEARCH ARTICLE Open Access MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: a case- control study in a population from North Sardinia Matteo Floris1*†, Daria Sanna1†, Paolo Castiglia2, Carlo Putzu3...
To evaluate the relationship between dietary folate intake and genetic polymorphisms of 5,10-methylenetetrahydrofolate reductase (MTHFR) with reference to breast cancer risk, we conducted a case–control study with 669 cases and 682 population-based cont
MTHFR基因 C667T位点多态性与亚洲人群乳腺癌易感性的 Meta分析张之涛 1 ,杨仲俊 1 ,王晓琼 2 ,闫鹏1AssociationbetweenMTHFRC667TpolymorphismandthesusceptibilityofbreastcancerinAsianpopulation:AMeta-analysisZhangZhitao1,YangZhongjun1,WangXiaoqiong2,YanPeng11DepartmentofOncologySurgery;2GalactophoreDepartment,Zhangye...
DUCTASEGENEANDSUSCEPTIBILITYTOBREASTCANCER LINJintai,CHENShengqiang,LIWeidong 【摘要】 目的 探讨代谢叶酸的亚甲基四氢叶酸还原酶(MTHFR)基因单核苷酸多态与乳腺癌风险 的关系。方法 以聚合酶链反应和限制性片段长度多态方法,分析了65个乳腺癌病人和143个正常对照的 ...
Breast cancer is the most common cancer affecting women in China and the world. Folate supplementation is proven to be effective in reducing the risk of br
Accumulating evidence from epidemiologic studies suggests that risk of breast cancer is reduced in relation to increased consumption of folate and related B vitamins. We investigated independent and joint effects of B vitamin intake as well as two polymorphisms of a key one-carbon metabolizing gene [...
There was a significant difference of MTHFR genetic polymorphism haplotypes among breast cancer cases and controls [cases/control: CA: 38.3/45.4%; CC: 28.9/25.2%; TA: 29.2/21; TC: 3.6/8.3; p value=0.01; ORTA vs. CA=1.6; 95% CI (1.1-2.5); p=0.02]. Genetic polymorphism of MTHFR C...
[3]. Sohn, K.J., et al., Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. J Natl Cancer Inst, 20 [4]. Etienne, M.C., et al., Methylenetetrahydrofolate reductase gene polymorphisms ...