Extracellular vesiclesMicroRNA deliveryTargeted therapyCancer remains a prominent worldwide health concern, presenting existing therapies with frequent difficulties, including major toxicity, limited effectiveness, and treatment resistance emergence. These issues highlight the necessity for novel and enhanced ...
Vesicles 2017, 6, 1265291. [CrossRef] [PubMed]Yuan Z, Kolluri KK, Gowers KH, Janes SM. Trail delivery by msc-derived extracellular vesicles is an effective anticancer therapy. J Extracell Vesicles 2017;6(1):1265291. doi: 10.1080/20013078.2017.1265291...
More recently, MSCderived extracellular vesicles (EVs), which include exosomes and microvesicles (MV), are being examined for their role in MSC-based cellular therapy. These vesicles are involved in cell-to-cell communication, cell signaling, and altering cell or tissue metabolism at short or ...
Advances have already been made towards the translation of MSC-derived extracellular vesicle in regenerative therapy. Moreover, according to preclinical studies, MSC-derived extracellular vesicles may have a promising role in the medical management of radiation injuries. Current and future perspectives on...
Harnessing the regenerative, immunomodulatory, and anti-inflammatory potential of MSC-derived Extracellular VesiclesAegle Therapeutics is a pioneer in regenerative medicine developing extracellular vesicle (EV) therapy to meaningfully improve the lives of those suffering from debilitating rare diseases, including...
Extracellular vesicles from mesenchymal stromal cells (MSC-EVs) have shown promise in wound healing. Their use in diabetic wounds specifically, however, re
Mesenchymal Stem Cell (MSCs) and MSC-Derived Extracellular Vesicles: Roles in Regenerative Medicine and Beyond Sections Figures References Abstract Introduction Wound healing process MSCs and MSC-derived exosomes: focus on wound healing Biomimetic scaffolds for delivery of MSCs and MSC-derived exosomes ...
MSC: Mesenchymal stromal/stem cell MSC-EV: MSC-derived extracellular vesicles OA: Osteoarthritis PBS: Phosphate-buffered saline PL: Platelet lysate RL/RR: Rear left/rear right ROI: Region of interest TNF: Tumor necrosis factor
As one of the main functional forms of mesenchymal stem cells (MSCs), MSC-derived extracellular vesicles (MSC-EVs) have shown an alternative therapeutic option in experimental models of allergic asthma. Oxygen concentration plays an important role in the self-renewal, proliferation, and EV release ...
Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer’s disease. Int Immunol. 2017;29(1):11–9. Article CAS PubMed Google Scholar Jung JW, Kwon M, Choi JC, Shin JW, Park IW, Choi BW, et al. Familial occurrence of pulmonary embolism after ...