Extracellular vesicles (EVs) and particles (EPs) have recently emerged as active carriers of molecular biomarkers and mediators of intercellular communication. While most investigations have focused exclusively on the protein, lipid and RNA constituents of these extracellular entities, EV/EP DNA remains ...
Moreover, we deconvoluted the heterogeneity of extracellular nanoparticles, defining three distinct subpopulations, small exosomes (Exo-S), large exosomes (Exo-L), and exomeres (Zhang and Lyden, 2019) that we collectively refer to as extracellular vesicles and particles (EVPs). Mounting evidence ...
1.Tumour extracellular vesicles and particles induce liver metabolic dysfunction. 肿瘤细胞外囊泡和颗粒诱导肝脏代谢功能障碍。 [Nature] PMID: 37225988 摘要:癌症改变了多个器官的功能,超出了转移所针对的器官。在这里,我们表明炎症、脂肪肝和代谢失调...
These particles are known as extracellular vesicles (EVs) and include species of exosomes and shed microvesicles. EVs carry molecules such as oncoproteins and oncopeptides, RNA species (for example, microRNAs, mRNAs, and long non-coding RNAs), lipids, and DNA fragments from donor to recipient ...
Extracellular Vesicles and Circulating Nucleic Acids, Editor-in-Chief Yoke Peng Loh, is a peer-reviewed journal dedicated to in-depth research into the molecular and cellular biology, biogenesis, and origins of extracellular vesicles or exosomes and circ
Extracellular Vesicles in Liver Pathobiology: Small Particles With Big Impact Abbreviations: ALIX, apoptosis-linked gene-2 interacting protein X; CCA, cholangiocarcinoma; CD, cluster of differentiation; CTGF, connective tissue growth factor; CXCL10, chemokine (C-X-C motif) ligand 10; ESCRT, endosomal...
Guest editors: Zhenhua Li, Honglin Jin, Lang Rao, and Chao Wang Extracellular vesicles (EVs) are nano-sized particles with bilayer lipid membranes, naturally secreted by almost all cell types. These vesicles can mediate cell-cell communication, regulate various signaling pathways by transporting biomo...
Malkin EZ, Bratman SV. Bioactive DNA from extracellular vesicles and particles. Cell Death Dis. 2020.https://doi.org/10.1038/s41419-020-02803-4. ArticlePubMedPubMed CentralGoogle Scholar Sharma A, Johnson A. Exosome DNA: Critical regulator of tumor immunity and a diagnostic biomarker. J Cell...
“extracellular vesicles” as a broad term for nano-sized particles that are normally produced by the cells and are bordered by a lipid bilayer. The current guidelines of ISEV classify the EVs on the basis of (i) size into small EVs (sEVs: diameter of < 200 nm) and medium/large EVs ...
Feb 2023 1被引用 0笔记 摘要原文 In recent decades, extracellular vesicles have been recognized as “very important particles” (VIPs) associated with aging and age-related disease. During the 1980s, researchers discovered that these vesicle particles released by cells were not debris but signaling ...