1.Tumour extracellular vesicles and particles induce liver metabolic dysfunction. 肿瘤细胞外囊泡和颗粒诱导肝脏代谢功能障碍。 [Nature] PMID: 37225988 摘要:癌症改变了多个器官的功能,超出了转移所针对的器官。在这里,我们表明炎症、脂肪肝和代谢失调...
These particles are known as extracellular vesicles (EVs) and include species of exosomes and shed microvesicles. EVs carry molecules such as oncoproteins and oncopeptides, RNA species (for example, microRNAs, mRNAs, and long non-coding RNAs), lipids, and DNA fragments from donor to recipient ...
Feb 2023 1被引用 0笔记 摘要原文 In recent decades, extracellular vesicles have been recognized as “very important particles” (VIPs) associated with aging and age-related disease. During the 1980s, researchers discovered that these vesicle particles released by cells were not debris but signaling ...
Profiling and promise of supermeres. Nat. Cell Biol. 23, 1217–1219 (2021). Article CAS PubMed PubMed Central Google Scholar Lucotti, S., Kenific, C. M., Zhang, H. & Lyden, D. Extracellular vesicles and particles impact the systemic landscape of cancer. EMBO J. 41, e109288 (...
Extracellular Vesicles in Liver Pathobiology: Small Particles With Big Impact Abbreviations: ALIX, apoptosis-linked gene-2 interacting protein X; CCA, cholangiocarcinoma; CD, cluster of differentiation; CTGF, connective tissue growth factor; CXCL10, chemokine (C-X-C motif) ligand 10; ESCRT, endosomal...
Circulating extracellular vesicles (EVs) are small, lipid-bound membrane-enclosed particles that carry various cell-derived biomolecules, such as DNA, RNA, proteins, and metabolites. They are released from different organs, tissues, and cell types, and can have local or systemic effects. EVs have...
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural carriers for therapeutic agents and drugs, and have many advantag
Extracellular Vesicles and Circulating Nucleic Acids, Editor-in-Chief Yoke Peng Loh, is a peer-reviewed journal dedicated to in-depth research into the molecular and cellular biology, biogenesis, and origins of extracellular vesicles or exosomes and circ
Extracellular Vesicles and Circulating Nucleic Acids, Editor-in-Chief Yoke Peng Loh, is a peer-reviewed journal dedicated to in-depth research into the molecular and cellular biology, biogenesis, and origins of extracellular vesicles or exosomes and circ
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as extracellular vesicles (EVs), into their surroundings to enable intercellular communication. EVs have numerous functions in physiological and pathophysiological processes and show considerable promise for diagnostic and ther...