We uncover axes of cell differentiation that are not apparent from single-cell RNA-sequencing (scRNA-seq) data, such as early dorsal–ventral separation of esophageal and tracheal progenitor populations in the gut tube. Our method provides an approach for studying cell fate decisions in complex ...
MoG+ also enables use of gene symbols as hubs to search for human disease information and mouse models available from RIKEN BRC. Introduction to MoG+ The top page of MoG+ is shown in Fig. 4a. The update to the database has added new features; thus, all strains in the Mishima...
The Mouse Genome Informatics (MGI) database system combines multiple expertly curated community data resources into a shared knowledge management ecosystem
However, the eQTL strength of these hair follicle keratins and T cell markers was similar in both tail and dorsal skin (Figure 1E). There was not a significant correlation between the difference in gene expression levels and the difference in eQTL strength. The peaks of almost all eQTL ...
(CPM) centered expression values in each lineage. The number of lineage-specific genes shown is indicated on the left, up to 200 genes are shown per lineage. For each lineage, 8 genes with the highest expression in the respective cell line are labeled.cLineage-specific gene expression ...
The purpose of this work was to study the gene expression of transient receptor potential (TRP) channels in the mouse. The application of a standardized and quantitative technique, TaqMan RT-PCR, should give information about the pattern and relative imp
A comprehensive analysis for tooth regenerative medicine is required to investigate the cell heterogeneity and gene expression/regulation dynamics in incisors and molars before birth. Therefore, we proposed to create a cell atlas of the whole tooth germ in varied development stages in single cell ...
In the field of mouse genetics the advent of technologies like microarray based expression profiling dramatically increased data availability and sensitivity, yet these advanced methods are often vulnerable to the unavoidable heterogeneity of in vivo material and might therefore reflect differentially expressed...
in E14 cell line-derived EBs at day 14. Left bottom, Western blot analysis showing STRAP expression in inducible STRAP knockdown EBs with ß-Actin as a loading control. For (i, m), and (o), PSI values are shown below gel pictures. Experiments were repeated three independent times with ...
W. V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets. Nat. Biotechnol. 28, 348–353 (2010). CAS PubMed PubMed Central Google Scholar Richardson, L., et al. EMAGE mouse embryo spatial gene expression database: (2014 update). Nucleic...