& Zou, J. Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures. Elife 10, e62293 (2021). CAS PubMed PubMed Central Google Scholar Finak, G. et al. MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in...
et al. A single-cell atlas of human and mouse white adipose tissue. Nature 603, 926–933 (2022). https://doi.org/10.1038/s41586-022-04518-2 Download citation Received15 May 2021 Accepted04 February 2022 Published16 March 2022 Issue Date31 March 2022 DOIhttps://doi.org/10.1038/s41586-...
52 Future exploitations of the single-cell atlas as a comparator are likely to include the analysis of single-cell transcriptomes from mouse models, including inducible mouse models of leukemia. When gene expression states are measured by using thousands of genes, progression of a cell through a ...
Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Sci Adv. 2018;4:eaao5508. PubMed PubMed Central Google Scholar Weber J, Öllinger R, Friedrich M, Ehmer U, Barenboim M, Steiger K, et al. CRISPR/Cas9 ...
We have used a number of banding techniques to analyze the chromosomal content of two sublines of the steroid-secreting mouse adrenocortical tumor cell line Y1. One of the sublines contains marker chromosomes with large "homogeneously staining regions" (HSRs). The other subline contains numerous ...
SJ Sawiak,P Jean-Luc,D Marc - 《Frontiers in Aging Neuroscience》 被引量: 8发表: 2014年 MRI Template and Atlas Toolbox for the C57BL/6J Mouse Brain In order to compare brain-imaging measurements from different subjects, brain-mapping algorithms are commonly used to register individual brain...
We established an efficient and simplified single-cell proteomics (ES-SCP) workflow to realize proteomics profiling at the single-oocyte level. With the ES-SCP workflow, we constructed a deep coverage proteome library during oocyte maturation, which contained more than 6000 protein groups, and identi...
These positions correspond to the superior colliculi as determined from a stereotactic mouse brain atlas. Three microliters of neurotracer dye 4-di-10-ASP at a concentration of 25 mg/ml were injected into superior colliculi through both holes 2 mm deep. The skull openings were then sealed with...
Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence3, genomic instability4 and changes in the immune system2. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides ...
To facilitate the use of our single-cell datasets, an online tool was generated for evaluation of gene expression at single-cell resolution:www.brainimmuneatlas.org. All gene–cell count matrices can also be downloaded via this link. In addition, all scRNA-seq and bulk RNA-seq data are also...