We have started generating metabolome atlases of normal healthy populations to serve as a reference database for future studies. We here present the atlas of the aging mouse brain with an emphasis on the anatomical resolution of 10 brain regions and temporal coverage over the life period from ado...
The results offer insight into the cognitive decline of normal aging, as well as the way aging contributes to neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases and multiple sclerosis. This research is published inCell, in the paper, “Atlas of the aging mouse brain re...
A metabolome atlas of the aging mouse brainJun DingJian JiZachary RabowOliver Fiehn
A metabolome atlas of the aging mouse brain Article Open access 15 October 2021 Meta-connectomic analysis maps consistent, reproducible, and transcriptionally relevant functional connectome hubs in the human brain Article Open access 04 October 2022 BrainTACO: an explorable multi-scale multi-modal...
However, there are limited data on the unique features and functions of fetal mucosal immune cells. To address this gap, we integrated several single-cell ribonucleic acid sequencing datasets of the human small intestine (SI) to create an SI transcriptional atlas throughout the human life span, ...
Thus far, the teams have identified more than 3,300 cell types. And as the resolution gets even higher (that’s what they’re working on now), they’re likely to uncover many more. Efforts to develop an atlas of the mouse brain, which are further along, have identified 5,000 cell ty...
Aging of the human brain is associated with "normal" functional, structural, and molecular changes that underlie alterations in cognition, memory, mood and... C Glorioso,E Sibille - 《Progress in Neurobiology》 被引量: 96发表: 2011年 Bisphenol A induces differentiation of human preadipocytes in...
The Allen Brain Atlas, a Web-based, genome-wide atlas of gene expression in the adult mouse brain, was an experiment on a massive scale. The development of the atlas faced a combination of great technical challenges and a non-traditional open research model, and it encountered many hurdles ...
By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.