The mammalian brain relies on neurochemistry to fulfill its functions. Yet, the complexity of the brain metabolome and its changes during diseases or aging remain poorly understood. Here, we generate a metabolome atlas of the aging wildtype mouse brain f
A metabolome atlas of the aging mouse brainJun DingJian JiZachary RabowOliver Fiehn
Dominant components of the Thoroughbred metabolome characterised by H-1-nuclear magnetic resonance spectroscopy: A metabolite atlas of common biofluids Reasons for performing studyMetabonomics is emerging as a powerful tool for disease screening and investigating mammalian metabolism. This study aims to cr....
A metabolome atlas of the aging mouse brain Article Open access 15 October 2021 White matter lipidome alterations in the schizophrenia brain Article Open access 26 December 2024 Meta-connectomic analysis maps consistent, reproducible, and transcriptionally relevant functional connectome hubs in the ...
Ant colonies with permanent division of labour between castes and highly distinct roles of the sexes have been conceptualized to be superorganisms, but the cellular and molecular mechanisms that mediate caste/sex-specific behavioural specialization have
approach. Using a technique called single-cellRNAsequencing that detects a large fraction of the RNA molecules (transcriptomes) present in single cells, the scientists generated a cell-type atlas of the brain of the Australian bearded dragonPogona vitticepsand compared it to existing mouse brain ...
However, there are limited data on the unique features and functions of fetal mucosal immune cells. To address this gap, we integrated several single-cell ribonucleic acid sequencing datasets of the human small intestine (SI) to create an SI transcriptional atlas throughout the human life span, ...
Sex-specific traits and behaviors emerge during development by the acquisition of unique properties in the nervous system of each sex. However, the genetic events responsible for introducing these sex-specific features remain poorly understood. In this s
Super-functional remote packs a wireless mouse, trackpad and laser beam January 21, 2025 |Ben Coxworth There are wireless computer mice, touchpads, TV remotes, and laser pointers … and then there's the Xring D13. It combines all of those tools in one wireless device, which could be yo...
Ovarian aging leads to diminished fertility, dysregulated endocrine signaling and increased chronic disease burden. These effects begin to emerge long before follicular exhaustion. Female humans experience a sharp decline in fertility around 35 years