关键词: Plasma Cells Lymphocytes Bone Marrow Humans Paraproteinemias Immunoglobulin kappa-Chains Immunoglobulin lambda-Chains DOI: doi:10.1111/j.1365-2141.1990.tb02606.x 被引量: 7 年份: 1990 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Semantic Scholar NCBI Europe PMC NCBI ResearchGate 查看更多...
Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PerCP-Cyanine5.5 浓度: 5 µL/Test 用法: 5 µL (0.125 µg)/test (Flow) 产品详细信息 Description: The CD28.2 monoclonal antibody reacts with the human CD28 molecule, a 44 kDa homodimer expressed by thymocytes, mature T cells and pla...
In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor ...
incurability remains an ongoing clinical challenge1. MM is characterised by the expansion of malignant monoclonal plasma cells (PCs) within the bone marrow (BM), and production of excess monoclonal immunoglobulin (M protein) and/or isotype-restricted free light chains (FLC)2,3. ...
Monoclonal antibodies are increasingly used to prevent and treat viral infections and are pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and plasmablasts) are an excellent source of high-affinity antibodies with therapeutic potential. Current methods to study antigen-...
CD30. CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class swit...
CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, ...
MM – is a malignant disease caused by neoplastic monoclonal proliferation of bone marrow plasma cells, characterized: ? plasma cell accumulation in the BM ? presence of MIG in the serum and/or urine ? specific organ dysfunction (CRAB) (hyper-Calcaemia, Renal damage, Anaemia and by Osteolytic...
Monoclonal gammopathy of undetermined significance(MGUS) is thought to be a precursor condition for myeloma, defined by the presence of monoclonal plasma cells with less than 10 % involvement of the bone marrowSethi et al., 2018;Kyle et al., 2006. The term of monoclonal gammopathy of renal s...
Plasma CellsLymphocytesBone Marrow CellsHumansSjogren's SyndromeImmunoglobulin ARheumatoid FactorBlood ViscosityMiddle AgedFemaleThe clinical features and results of serological studies of a patient with Sj枚gren's syndrome, IgA kappa monoclonal gammopathy, and hyperviscosity syndrome are reported. The novel...