Circulating bladder tumor cells provide significant information for cancer diagnosis, tumor staging and personalized cancer therapy. Previous studies have reported various methods for capturing circulating tumor cells; however, capturing circulating tumor cells remain a challenge. Here, we present a ...
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.doi:10.1172/JCI66776The use of monoclonal antibodies (mAbs) as therapeutic tools has increased dramatically in the last decade and is now one of the mainstream strategies to treat cancer. Nonetheless, it is still not ...
The meaning of MONOCLONAL is produced by, being, composed of, or caused by cells derived from a single cell; especially : relating to, being, or caused by a monoclonal antibody or monoclonal antibodies. How to use monoclonal in a sentence.
In response to mAb therapy, we have identified macrophages in the liver as major effector cells removing circulating tumor cells via antibody-dependent phagocytosis, an immune cell-mediated process that prevented liver metastasis. This discovery extends our understanding of the mechanisms of mAb therapy...
Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection. "Published figure using CD45 monoclonal antibody (Product # 69-0459-42) in Flow Cytometry" 4.Journal of biological research (Thessalonike, Greece) ...
Tumor microenvironment Circulating tumor cells Cell and gene therapy overview CAR T cell manufacturing T cell engineering by electroporation and transduction (GMP) Regulatory T cells for immunotherapy Virus-specific T cells for immunotherapy Clinical-grade tumor-reactive T cell manufacturing NK cells for ...
Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection. "Published figure using CD45 monoclonal antibody (Product # 69-0459-42) in Flow Cytometry" 4.Journal of biological research (Thessalonike, Greece) ...
tumor cell depletion by mouse IgG2a monoclonal antibody against CD20 required the interaction with Fc receptors on macrophages[50]. Recent clinical work by Marjolein van Egmond and associates likewise showed that macrophages eliminate circulating tumor cells after monoclonal antibody therapy[51]. Other ...
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implic...
The level of free idiotype had not substantially altered, there was no increase in the level of circulating tumor cells, and there was no anti-mouse antibody in the serum. Antibody titer and affinity were not different. The phenomenon of transient falls in the circulating tumor cells resulting ...