Monoclonal vs Polyclonal Antibodies Lesson Summary Frequently Asked Questions What are examples of polyclonal antibodies? Some examples of polyclonal antibodies include certain cancer treatments that can target various tumor cells. Like immunoassays such as ELISA which are frequently used in research, and...
In recent years, the use of both polyclonal and monoclonal antibodies has increased significantly. Each type of antibody has its own advantages and disadvantages, many of which may be weighted differently by the antibody developer and the end-user. You'll recall that in past decades, academic re...
OncologyWobbes et al. " The Squamous Cell Carcinoma Tumor Marker in Mammary Carcinoma: Comparison of Polyclonal versus Monoclonal Antibody-Based Assays "; Department of General Surgery and Obstetrics and Gynecology, Universith Hospital Nijmegen, The Netherlands; Oncology 1990; pp. 14-18....
P_poly, polyclonal polyp; P_mono, monoclonal polyp; T_poly, polyclonal tumor; T_mono, monoclonal tumor. AMP, amplification; DEL, deletion. wGII, weighted genome instability index. CIN, chromosomal instability. Extended Data Fig. 7 Whole-genome sequencing (WGS) of 32 single glands from normal...
Purified monoclonal mouse or polyclonal horse antibodies (Ab) to rat alpha-fetoprotein (AFP) were conjugated with daunomycin via a dextran bridge. The therapeutic effect of these Ab-daunomycin conjugates on an AFP-producing rat hepatoma which was inoculated s.c. in Donryu rats was studied. T...
The mean tumor volume after 20 days was 1730 ± 399 mL vs. 2739 ± 707 mL (P < 0.01, n = 7). *P < 0.05; **P < 0.01; ***P < 0.001. Full size image Antitumor effects of the (P)RR Ab on engrafted U87MG cells To examine the effects of the ...
Normal human peripheral blood cells were stained with 0.5 µg of Mouse IgG2a kappa Isotype Control (Product # 14-4724-82) (blue histogram) or 0.5 µg of HLA-ABC Monoclonal Antibody, Functional Grade (purple histogram) followed by IgG Polyclonal Antibody, PE (Product # 12-4010-87) . Ce...
Western blot was performed using anti-IKKG Polyclonal Antibody(Product # MA1-41219) a 48 kDa band corresponding to IKKG was observed across the cell lines tested. Additional un-characterized bands (*) were observed (a band around 36 kDa could be the probable isoform of IKKG). Whole cell ...
Sandwich ELISA of Apolipoprotein A-1 was performed by coating wells of a 96-well plate with 100 µL of an Apo A-1 Recombinant Rabbit Polyclonal Antibody (Product # 710263) at a concentration of 1 µg/mL in carbonate/bicarbonate buffer (Product # 28382) overnight at 4C. Wells were bl...
The polyclonal antibodies can be replaced by a second enzyme-conjugated monoclonal antibody of the invention which recognizes a different epitope of hirudin than the first carrier-bound monoclonal antibody. There is also preferred an ELISA in which the carrier is coated with a monoclonal antibody ...