Nakamura, K., and Knight, R.A. 1982. Intranuclear incorporation of thymic low molecular weight RNA by murine bone marrow immunoblasts and inhibition of plasma cell formation by a derivative of rifampicin. Microbiol. Immunol. 26: 41-57.
Rifampicin, which was shown to act synergistically with ADEP against S. aureus (Conlon et al., 2013), is widely used against M. tuberculosis and another interesting option could be a combination of ADEP with streptomycin, as down-regulation of clpP1P2 expression in M. smegmatis increased ...
Following addition of 0.5 mg/mL rifampicin, cells were incubated for 1 hr at 37°C, 400 rpm (3 mm orbit), 0.2 mM isopropyl-β-D-thiogalactoside (IPTG) was added and cells were incubated for a further 5 min. Samples were ‘pulsed’ by addition of 22 μCi mL−1 [35S]-methionine ...
[31,75–78] In the latter case, polyesters, specifically PLLA, have been the most widely used for encapsulating drugs, such as para-hydroxybenzoic acid,[31] chlorpheniramine and indomethacin,[79] gentamicin, naloxone and naltrexone,[80] bupivacaine,[81] rifampicin[82] and paracetamol,[83] and...
Passive membrane permeability of sizable acyclic β‐hairpin peptides. ACS Med. Chem. Lett. 14, 278–284 (2023). Article CAS PubMed Google Scholar Ermondi, G. et al. Managing experimental 3D structures in the beyond-rule-of-5 chemical space: the case of rifampicin. Chem. Eur. J. 27...
Remarkably, the conjugate 4f demonstrated similar potency against rifampicin and multidrug resistant mycobacterial strains while exhibiting little toxicity against normal cells. In vivo studies demonstrated the promising potential of the conjugate for further development. Finally, a molecular docking study was...
MeNP 129.2 Rifampicin 26.5 73.1 1.8 46.8 NNV 240.3 Varenicline 37a 112.1 2.1 79.3 NMPH 262.3 Methyl-phenidate 1300 114.2 2.3 2986 Nitroso-nortriptyline 292.4 Amitriptyline 8b 164.2 1.8 14.2 Nitroso-duloxetine 326.4 Duloxetine 100 207.2 1.6 157.5 Nitroso-fluoxetine 338.3 Fluoxetine 100 207.2 1.6 163.3...
The viral proteins synthesized in non-suppressor cells by amber mutants in the A protein cistron of the RNA bacteriophage MS2 were analyzed. Protein synthesis was studied in rifampicin-inhibited cultures and the labeled, viral proteins were separated on sodium dodecyl sulphate containing polyacrylamide ...
(Georghiou et al.2023; Su et al.2019). Mutations in genes such asrrl,rpoB,gyrA, andgyrBare responsible for instilling resistance to linezolid (LZD), rifampicin (RIF), and levofloxacin (Akrami et al.2023; Chien et al.2016). Additionally, other genes such aspepQ,crfA,Rrs, andrrscan ...
(c): rifampicin treatment (n = 3). (d) Growth curves for cultures starved for glucose, phosphate or treated with 100 µg/ml of rifampicin. The vertical line indicates time of filtration and resuspension in starvation medium (red or blue curve), or rifampicin treatment (orange curve). To...