2041-4889/12 www.nature.com/cddis Molecular targeting of NOX4 for neuropathic pain after traumatic injury of the spinal cord YB Im1, MK Jee1, JI Choi1, HT Cho1, OH Kwon1 and SK Kang*,1 Neuropathic pain is a well-known type of chronic pain caused by damage to the nervous system. ...
The role of nox-mediated oxidation in the regulation of cytoskeletal dynamics. Curr. Pharm. Des. 21, 6009–6022 (2015). Article CAS PubMed PubMed Central Google Scholar Perez-Sala, D. & Quinlan, R. A. The redox-responsive roles of intermediate filaments in cellular stress detection, ...
Levels of the low molecular weight GTP-binding protein G27K in erythrocyte membranes of patients with coronary atherosclerosisHigh NOx levels are the risk factors of cardiovascular death in the elderly in a 7-year follow-up studydoi:10.1016/0021-9150(94)93747-8A. Kots...
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Nox4-generated ROS Regulate TGF-β1-induced Motility of Colon Cancer Cells through the Low Molecular Weight Protein Tyrosine Phosphatase-Rho Signaling Pathway Nitric oxide synthase (NOS) activity and NO-mediated cGMP synthesis were studied in the rat forebrain of control animals and animals which had...
Taken together, the exact role of NOX2 in obesity-induced insulin resistance across various tissues remains unclear; mouse strain-specific differences in ambulatory physical activity or muscle mass could explain these discrepancies. Exercise training promotes weight maintenance and improves whole-body ...
(ROS) production by the NADPH oxidase NOX2, and secretion of the proinflammatory chemokine IL-8 and the B-cell-activating cytokine BAFF [235]. Of note, many known NET inducers, such as IL-1β, IL-8, TNF, and G-CSF are increased in COVID-19 patients [236]. Additionally, histones, ...
Samples of the aerosol particles generated from these gas phase reactions were collected on stainless steel disks using a specially-designed impactor. The samples were analyzed using computer-controlled high resolution mass spectrometry. The photochemical reaction of limonene with NOx produced more than ...
[211,226]. The multiple and arguably pivotal roles of the latter include the regulation of NET production, autophagy, oxidative burst, phosphorylation, and stabilization of NOX and HIF1α [226,227]. mTOR also increases the surface expression of GLUT-1 and intensifies mitochondrial biogenesis and ...
Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the prevention and treatment of various diseases, the underlying biological mechanisms have not been fully elucidated. Several exercise benefits have been attributed to sig