This chapter focuses on the molecular mechanism of action (MMoA) in drug discovery. MMoA of a medicine is the connection of the molecular interactions between the therapeutic treatment and the biological target that yields the physiological response. Mechanism-based toxicity is a potential concern ...
网络释义 1. 分子作用机制 分子作用机制,molecular mechanism... ... )molecular mechanism of action分子作用机制) molecular mechanism 分子作用机制 ... www.dictall.com|基于 1 个网页
2) molecular mechanism 分子作用机制 1. This article reviews the development,clinicalapplication,QSAR studies of bisphosphonates,and describes recent new discoveries of their molecular mechanism of action in osteoclast. 双膦酸盐类化合物是防治骨代谢疾病的重要药物 ,本文对双膦酸盐类药物的临床应用、构效...
Molecular mechanism of action at estrogen receptor alpha of a new clinically relevant antiestrogen (GW7604) related to tamoxifen. Molecular mechanism of action at estrogen receptor α of a new clinically relevant anti-estrogen (GW7604) related to tamoxifen. Endocrinology, 2001, 142(2......
2. Preparation of antihypertensive peptides from food proteins 3. Molecular mechanisms of action of food protein-derived antihypertensive peptides 4. Previously recognized mechanism of blood pressure lowering by bioactive peptides 5. Recently recognized mechanisms of suppressing blood pressure by bioactive ...
Yinchen Wuling powder is often used to treat clinical hyperlipidemia, although its mechanism of action remains unclear. In this study, we aimed to investigate the active ingredients found in Yinchen Wuling powder and find its mechanism of action when treating hyperlipidemia, using a combination of ...
Iconography : Elucidation of the molecular mechanism of action of selective estrogen receptor modulators American Journal of Cardiology, The - Vol. 90 - N° 1S1 - p. F35-F43 - Iconography : Elucidation of the molecular mechanism of action of selective estrogen... DP Mcdonnell,A Wijayaratne,C...
Molecular mechanism of action of plant DRM de novo DNA methyltransferases. Cell 157, 1050–1060 (2014). Article PubMed Central CAS PubMed Google Scholar Gao, Z. et al. An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA methylation. Nature 465, 106–109 (2010)....
mechanism of action is dictated by the structural features of the molecules involved, the system in which they are present as well as processing and storage conditions, among others. While much research has been carried out on this type of chemical systems, there are still many questions to be...
The molecular mechanism of action of clostridium perfringens type A enterotoxin: Morihiro Matsuda1, Nakaba Sugimoto1, Kunihiro Ozutsumi1 and Masayuki Takagi2 (1Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita 565; and 2College of General Education, 1-1 Machikaneya...