近2年刘丽梅教授和翁建平教授团队分别进行MODY相关研究并发表文章,提示MODY2(GCK)、MODY3(HNF-1α)可能是中国人群最常见的MODY类型,并进行了更深入的工作,其研究为我国人群MODY流行病学提供了一些参考。 其中,2020年8月翁建平教授团队...
Type 1 diabetes is one of the most common chronic disorders in childhood and adolescence. Evidence based guidelines from the German Diabetes Society (Deutsche Diabetes Gesellschaft) and the German Society for Childhood and Adolescent Medicine (Deutsche Gesellschaft f眉r Kinderheilkunde und Jugendmedizin)...
糖尿病是一组由环境、遗传因素和健康行为相互作用而产生的复杂的临床综合征,其中遗传因素在糖尿病尤其在2型糖尿病(type 2 diabetes,T2DM)的发病中所起的作用更是日益受到人们的重视。目前认为,T2DM在家族遗传中个体在具有遗传背景的基础上,如再暴露于一个或多个环境危险因素,必将大大增加个体对糖尿病的患病危险性,...
Maturity-onset diabetes of the young or MODY is considered by many physicians and researchers to be a subset of Type 2 diabetes (T2D) and is often misdiagnosed as T2D.
[关键词]糖尿病,2型;基因;变异(遗传学) [中图分类号]R587.1[文献标识码]A[文章编 号]1671—167X(2005)06-0591-04 ContributionofMODY2genetothepathogenesisofChineseearlyonsetfamil ialtype 2diabetes HANXue—yap,JILi—nong (DiabetesCenterofPekingUniversity,DepartmentofEndocrinologyandMe ...
DiabetesCare:青少年成熟期糖尿病(MODY),不是1型,也不是2型糖尿病! 单基因糖尿病,包括青少年成熟期糖尿病(MODY),是由单一基因异常导致的糖尿病。单基因糖尿病可由破坏葡萄糖感应、胰岛素转录、传递胰岛素释放信号的KATP通道、胰岛素基因或胰腺发育的基因突变引起。正确诊断单基因糖尿病对管理、预测并发症和家族风险都...
Type 2 diabetesGenome-wide association studies have identified 240 independent loci associated with type 2 diabetes (T2D) risk, but this knowledge has not advanced precision medicine. In contrast, the genetic diagnosis of monogenic forms of diabetes (including maturity-onset diabetes of the young (...
A Clinical Prediction Model to Distinguish Maturity-Onset Diabetes of the Young From Type 1 and Type 2 Diabetes in the Chinese Population. Endocr Pract. 2021;27(8):776-782. 作者 付俊玲#,平凡#,王彤,刘艺文,王晓晶,余洁,邓明...
HDL-cholesterol: differentiating between HNF-1alpha MODY and type 2 diabetes. Diabetic Medicine . 2003; 20 (supplement 2, article 15)E. Pearson, J. McEneny, I. Young, and A. Hattersley, "HDL- cholesterol: differentiating between HNF-1alpha MODY and type 2 diabetes," Diabetic Medicine, ...
2、Molecular Scanning on MODY Genes in Chinese Early Onset Familial Type 2 Diabetes 中国人早发2型糖尿病家系中MODY基因缺陷的分子筛查。3、Mody know, because my spring, in the summer.知道么，因为我的春天，在夏天。4、Is it, people are living in self-deceiving life Mody?难道、人都...