7.Stem cell therapy for Alzheimer’s disease: An overview of experimental models and reality 作者:Chuan Qin, Kewei Wang, Ling Zhang, Lin Bai 阿尔茨海默病干细胞疗法:实验动物模型的现况概述 Animal Model Exp Med. 2022 Feb;5...
Biomedical research is undergoing a paradigm shift towards approaches centred on human disease models owing to the notoriously high failure rates of the current drug development process. Major drivers for this transition are the limitations of animal models, which, despite remaining the gold standard in...
L. Mouse models of human disease: an evolutionary perspective. Evol. Med. Public Health 2016, 170–176 (2016). PubMed PubMed Central Google Scholar Shultz, L. D., Brehm, M. A., Garcia-Martinez, J. V. & Greiner, D. L. Humanized mice for immune system investigation: progress, ...
Mouse models mimicking human diseases are important tools in trying to understand the underlying mechanisms of many disease states. Several surgical models have been described that mimic human myocardial infarction (MI) and pressure-overload-induced cardiac hypertrophy. However, there are very few detail...
Mouse Models of Human Autoimmune Diseases: Essential Tools That Require the Proper Controls 来自 Semantic Scholar 喜欢 0 阅读量: 11 作者: L Morel 摘要: What can we learn about human autoimmune disorders that have a genetic component -- such as systemic lupus erythematosus -- from mouse ...
Animal Models for the Study of Human Disease, Second Edition,provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. ...
[MICCAI] Open-ended medical visual question answering through prefix tuning of language models.[Paper][Code] [arXiv] Qilin-Med-VL: Towards chinese large vision-language model for general healthcare.[Paper][Code] [arXiv] A foundational multimodal vision language AI assistant for human pathology.[...
Development of humanized mouse models to study human malaria parasite infection Malaria is a disease caused by infection with Plasmodium parasites that are transmitted by mosquito bite. Five different species of Plasmodium infect human... AM Vaughan,SH Kappe,A Ploss,... - 《Future Microbiology》 ...
Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism Shotaro Uehara , Yuichi Iida & Hiroshi Suemizu Article 01 July 2022 | Open Access Cardiovascular changes after pneumonia in a dual disease mouse model Benjam...
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have numerous shared characteristics between mice and humans. Human counterparts of mouse DC progenitors have been identified by their shared transcriptional signatures