In addition, the risk of the development of resistance and the incidence of certain side effects in the host organism can be assessed, though it is currently possible only to a moderate extent to derive a proposal for a useful combination therapy on the basis of the mode of action of the ...
Ruby, University of Southern California. Table I. MIC values for indolicidin Species and strainRelevant phenotypeMIC GentamicinPolymyxin BIndolicidinIndolicidin-C µg/ml E. coli UB1005 Parent of DC2 1 0.5 16 4 DC2 Polymyxin sensitive 0.5 0.1 4 4 P. aeruginosa H103 PAO1 strain 1 0.5 ...
Changes followed distinct patterns that correlated with mode of action: penicillin binding protein (PBP) 3 blockade (ceftazidime, piperacillin); PBP 2 blockade (imipenem); mem- brane disruption (colistin); bacteriostatic (chloramphenicol), and bactericidal (gentamicin) protein synthesis inhibition; and ...
Khameneh B, Iranshahy M, Ghandadi M, Ghoochi Atashbeyk D, Fazly Bazzaz BS, Iranshahi M (2015) Investigation of the antibacterial activity and efflux pump inhibitory effect of co-loaded piperine and gentamicin nanoliposomes in methicillin-resistantStaphylococcus aureus. Drug Dev Ind Pharm 41:989...
The antibacterial activities of the essential oil, and its major constituents, were evaluated against Streptococcus pyogenes, methicillin‑resistant Staphylococcus aureus (MRSA), MRSA (clinical strain), methicillin‑gentamicin resistant Staphylococcus aureus (MGRSA), Streptococcus pneumoniae, Klebsiella ...
SV40 HCEC kindly supplied by Araki-Sasaki were maintained in DMEM/F-12 supplemented with 6% fetal bovine serum, 5 ng/mL epidermal growth factor, 5μg/mL insulin and 40 μg/mL gentamicin in humidified 5% CO2, 95% ambient air incubator at 37 °C.79 Cells were grown to 80–90% confluenc...
concentration (MIC) of peptides and conventional agents against Acinetobacter baumannii strains. Microorganisms Microorganisms A. baumannii KCTC 2508 Minimum Inhibitory Concentration (µM) Magainin 2 MiBnuimfourminI2nhibMitoerlyitCtionncenCtriaptiroonfl(oµxMac)in Gentamicin Mag4ainin 2 Bufo8rin 2 ...
aureus ATCC 25923 was tested against gentamicin (A2712, VWR, Radnor, PA, USA). Tests were performed in triplicates with three technical replicates; median MIC values are displayed. 5.12. Data Analysis Data handling, analysis, statistics and presentation were done using R 4.1.0 [49], the ...
(6 mm in diameter) were separately impregnated with 15 μL of tested oil and placed on the agar which had previously been inoculated with the selected bacteria. Gentamicin (10 µg/disc) was used as a positive reference. Negative control corresponds to disc without sample. The inoculated ...