Gentamicin is a broad-spectrum aminoglycoside antibiotic that is most effective against aerobic gram-negative rods. It is also used in combination with other antibiotics to treat infections caused by gram-positive organisms such asStaphylococcus aureusand certain species of streptococci. Additionally, gent...
Spectrum of activity. The following pathogenic organ- isms are usually sensitive to gentamicin (but see also Resistance, below). Many strains of Gram-negative bacteria including spe- cies of Brucella, Calymmatobacterium, Campylo- bacter, Citrobacter, Escherichia, Enterobacter, Fran- cisella, ...
Gentamicin (Centicin) is a broad-spectrum aminoglycoside antibiotic with antibacterial activity, inhibiting the growth of Gram-positive and Gram-negative bacteria, and can be used to study ocular infections. 体外活性 Gentamicin溶于 EMEM,使用时的最终浓度为 200 μg/ml。所有细菌菌株在没有抗生素的情况...
In vitro spectrum of activity includes many gram-negative aerobic bacteria (including most Enterobacteriaceae and Pseudomonas aeruginosa) and some aerobic gram-positive bacteria. Inactive against fungi, viruses, and most anaerobic bacteria. Gram-positive aerobes: active in vitro against penicillinase-produc...
Define gentamicin. gentamicin synonyms, gentamicin pronunciation, gentamicin translation, English dictionary definition of gentamicin. n. A broad-spectrum antibiotic derived from an actinomycete of the genus Micromonospora, used in its sulfate form to tr
Gentamicin is an antibiotic that exhibits a broad spectrum of activity and is particularly valuable in severe sepsis. Its use is, however, restricted because of the development of ototoxicity and nephrotoxicity (for the latter, see review in Ref. 1). At physiologic pH, the drug is highly charg...
Chloramphenicol and tetracycline inhibited the bactericidal effect of gentamicin, whereas the combination of gentamicin with three penicillins, sul-phathiazole, polymyxin B, and streptomycin showed an additive effect by inhibiting regrowth of the test organism. The antibacterial spectrum of gentamicin was ...
indicating that the material is responsive to microbial activity. As exemplar drugs, vancomycin and gentamicin-eluting scaffolds were demonstrated to be bactericidal, and supported osteogenesis in vitro. In a pilot murine model of OM, vancomycin-eluting scaffolds were observed to reduce S. aureus infec...
Gentamicinis a widely utilizedantibioticin treatingosteomyelitisdue to its broad-spectrum properties.Gentamicinis effective against the majority of bacteria that causechronic osteomyelitis. This drug has been loaded into various scaffolds to test their ability to act as controlled-release carriers[141]. Th...
There was no indication of mutagenic activity. View all 3. Use and Manufacturing 3.1 Description Gentamicin, with the chemical formula C21H43N5O7, has the CAS number 1403-66-3. It is a broad-spectrum antibiotic belonging to the class of aminoglycosides. Gentamicin appears as a white to ...