5 The unpredictability of ototoxicity supports close monitoring of the patient throughout treatment.5 In cases of toxicity or overdose, the medication should be discontinued immediately; hemodialysis may be initiated to lower gentamicin serum concentrations.24 Pathways PathwayCategory Gentamicin Action ...
Gentamicin Doxycycline may decrease the excretion rate of Gentamicin which could result in a higher serum level. Gestrinone The serum concentration of Gestrinone can be decreased when it is combined with Doxycycline. Gimeracil Doxycycline may decrease the excretion rate of Gimeracil which could result...
1985. Mechanism of action of gentamicin components. Characteristics of their binding to Escherichia coli ribosomes. Eur J Biochem 147:381-386.Tangy F, Moukkadem M, Vindimian E, Capmau ML, Le Goffic F (1985). Mechanism of action of gentamicin components. Characteristics of their binding to ...
The cells were grown as monolayer cultures in Dulbecco’s modified Eagle’s medium with the antibiotic gentamicin (200 μL/100 mL medium) in 75 cm2 flasks (Nunc). The DMEM for the HCT116 were supplemented with 12% heat-inactivated fetal bovine serum (Sigma-Aldrich, St. Louis, MO...
auranofin exhibited an additive effect in inhibiting bacterial growth when combined with the antibiotics ciprofloxacin, linezolid and gentamicin (average fractional inhibitory concentration, FIC index = 0.5 to 1) (Fig. 5c). Thus the above results indicate auranofin is a potential candidate for fu...
Antimicrobial resistance is a major threat to human health. Basic knowledge of antimicrobial mechanism of action (MoA) is imperative for patient care and for identification of novel antimicrobials. However, the process of antimicrobial MoA identification
G Gentamicin Translation H Chloramphenicol Translation K Kanamycin Translation Li Linezolid Translation Pa Pactamycin Translation Pu Puromycin Translation Tan TAN 1057 Translation Y Azithromycin Translation Fatty acid biosynthesis inhibitors (FAB)a B Moiramide B Fatty acid biosynthesis (acetyl-CoA carboxylase...
Antibiotic-loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use. Biomaterials 2010, 31, 6363–6377. [71] Wahlig, H.; Dingeldein, E.; Buchholz, H.W.; Buchholz, M.; Bachmann, F. Pharmacokinetic study of gentamicin-...
L-glutamine (2 mmol/L), penicillin (100 U/mL) and streptomycin (100 mg/mL) at a ratio of 1:1, and gentamicin (10 mmol/L) in nonadherent tissue culture plates. The cells required 500 pmol/L recombinant human GM-CSF (rhGM-CSF. a gift from Larry Souza at Amgen, Thousand Oaks, CA...
Gentamicin Icosapent may decrease the excretion rate of Gentamicin which could result in a higher serum level. Gimeracil Icosapent may decrease the excretion rate of Gimeracil which could result in a higher serum level. Givosiran The risk or severity of nephrotoxicity can be increased when Icosapent...