Studies on the Mechanism of Action of Gentamicin. Effect on Protein Synthesis in Cell-Free Extracts of Escherichia coli* Addition of Gentamicin to exponentially growing cells of Escherichia coli strongly inhibits amino acid incorporation into protein while uracil incorporation into nucleic acid is not af...
1985. Mechanism of action of gentamicin components. Characteristics of their binding to Escherichia coli ribosomes. Eur J Biochem 147:381-386.Tangy F, Moukkadem M, Vindimian E, Capmau ML, Le Goffic F (1985). Mechanism of action of gentamicin components. Characteristics of their binding to ...
5 In cases of toxicity or overdose, the medication should be discontinued immediately; hemodialysis may be initiated to lower gentamicin serum concentrations.24 Pathways PathwayCategory Gentamicin Action Pathway Drug action Pharmacogenomic Effects/ADRs Not Available Interactions Drug Interactions This ...
Gentamicin The risk or severity of neuromuscular blockade can be increased when Gentamicin is combined with Clindamycin. Glecaprevir The metabolism of Clindamycin can be decreased when combined with Glecaprevir. Glofitamab The serum concentration of Clindamycin can be increased when it is combined with...
Gentamicin C 1a was a poor inhibitor. This suggested that either the kanosamin or garosamin rings might be determinant in the binding of these molecules, as well as the 6'-amino group.Franois GOFFICCentre d‘Etudes et de Recherches de Chimie Organique Appliquée du Centre National de la ...
auranofin exhibited an additive effect in inhibiting bacterial growth when combined with the antibiotics ciprofloxacin, linezolid and gentamicin (average fractional inhibitory concentration, FIC index = 0.5 to 1) (Fig. 5c). Thus the above results indicate auranofin is a potential candidate for fu...
Gentamicin is the most commonly used example, but others include neomycin and tobramycin. Coverage Aminoglycosides tend to be used for severe infections, especially those caused by Pseudomonas. They are also often combined with penicillins or metronidazole where the causative organism of severe infection...
- 《Journal of Pharmacobio Dynamics》 被引量: 50发表: 1984年 Effects of combinations of beta-lactams, daptomycin, gentamicin, and glycopeptides against glycopeptide-resistant enterococci. Activities of combinations of beta-lactams, daptomycin, gentamicin, teicoplanin, and vancomycin against 11 clinical ...
The cells were grown as monolayer cultures in Dulbecco’s modified Eagle’s medium with the antibiotic gentamicin (200 μL/100 mL medium) in 75 cm2 flasks (Nunc). The DMEM for the HCT116 were supplemented with 12% heat-inactivated fetal bovine serum (Sigma-Aldrich, St. Louis, MO...
To deplete original gut microbiota, recipient mice were pretreated with multiple antibiotics (1 g/L streptomycin, 0.5 g/L ampicillin, 1 g/L gentamicin, and 0.5 g/L vancomycin) according to Yin et al.84 Mice received antibiotics via the drinking water for 10 days and then were tested for ...