6) penicillins/ therapeutic use 青霉素类/治疗应用补充资料:6-N′-甲基庆大霉素 分子式:CAS号:性质:又名小诺霉素;相模霉素;6-N′-甲基庆大霉素;沙加霉素。由小单孢菌Micromonospora sagamiensis及其变异株产生的氨基糖苷类抗生素。常用硫酸盐,白色粉末,无臭,无味。易溶于水,不溶于有机溶剂。室温下稳定。半...
Background: The use of gentamicin places patients at risk of developing drug-induced nephrotoxicity, requiring special consideration to be given to serum creatinine monitoring and therapeutic drug monitoring (TDM).Mason, T.Verley, M.Gossell-Williams, M.Thorbourne, A.Walcott-Mitchell, A.Hoe, K....
Probable chromosomal mutation to resistance to all aminoglycosides in Staphylococcus aureus selected by the therapeutic use of gentamicin: a preliminary re... Probable chromosomal mutation to resistance to all aminoglycosides in Staphylococcus aureus selected by the therapeutic use of gentamicin: a ...
It is nevertheless concluded that the in-vitro inactivation of gentamicin is not a contraindication to the combined use of gentamicin and a penicillin or cephalosporin antibiotic in the treatment of serious sepsis, provided that they are not mixed in intravenous infusion fluids. Where large doses ...
An Enterococcus faecium isolate was found to be highly resistant to vancomycin and gentamicin. Sequence analysis suggested that this resistance was due to gene exchange between human and canine enterococci (2). The use of last-resort human antimicrobials in veterinary patients wit...
A role for superoxide in gentamicin-mediated nephropathy in rats Gentamicin is an antibiotic effective against Gram-negative infection, whose clinical use is limited by its nephrotoxicity. Oxygen free radicals are consid... S Cuzzocrea,E Mazzon,L Dugo,... - 《European Journal of Pharmacology》 被...
Bacterial infections have long been a scourge for humanity. In the past century, the discovery and widespread use of antibiotics have somewhat improved the treatment of these infections.1,2,3However, in recent decades, the emergence and increasing antibiotic resistance has heightened concerns regarding...
, efficient delivery of protein tools such as antibodies, binders, reporters and genome-editing proteins could facilitate their use in perturbing biological processes in their natural in vivo context. Delivery of natural endogenous or heterologous proteins of interest could enable direct study of their...
when several sheets of Sofratulle patch are used not for its intended use as the patch but are formed into a dumpling shape or folded depending on the size of the ulcer with a pocket, sprayed with Fiblast Spray 500 until sufficiently impregnated with a trafermin solution and are packed in...
The invention provides a compound of Formula (I): or salts, solvates or tautomers thereof, for use: a) in the prophylaxis or treatment of a disease state or condition mediated by a kinase, or a mutated form thereof, which isa member of the AXL family, or the PKC family, or the CSF...