Mixed connective tissue disease (MCTD) was described as a distinct clinical syndrome in 1972. Since then many cases have been reported in the literature worldwide. In this study we present our experience with a group of 17 Mexican patients with this syndrome, and we analyze their clinical and...
Sharp G.C., Irwin W.S., Tan E.M., Gould R.G., and Holman R.R.: Mixed connective tissue disease, an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen. Am. J. Med. 1972, 52, 148–159. Google Scholar Le Roy E.C.,...
A defining feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribonucleoprotein (RNP) complex, but other autoantibodies in MCTD have recently been described. Research has also further elucidated the immune responses directed against U1-RNP in humans and in...
(左) 患者冠状位NECT显示右上肺蜂窝样变(纤维化)及支气管扩张,伴下叶磨玻璃影;肺活检示非特异性间质性肺炎。(右) 横断位NECT显示支气管周围实变影、支气管扩张,少量胸腔积液及张开扩张的食管;活检提示机化性肺炎及非特异性间质性肺炎。 (左) 患者横断位NECT显示基底部网状影、细支气管扩张及伴胸膜下无累及区...
Mixed Connective Tissue DiseaseFragile-X-SyndromePurpose: To report an unusualcase of retinal microvasculopathy secondary to mixed connective tissue disease(MCTD) on a background history of fragile-X syndrome (FXS). Methods: Case report and literaturereview. Results: A cotton wool spotwas discovere...
Mixed Connective Tissue Disease (MCTD) - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
Mixed connective tissue disease (MCTD), or: Sharp syndrome, is an uncommon, specifically defined, overlap syndrome. MCTD should be suspected when additional overlapping features are present in patients appearing to have rheumatoid arthritis, SLE, scleroderma, or polymyositis. MCTD is characterised...
Mixed connective tissue disease (MCTD) is a systemic inflammatory disease affecting connective tissue with the underlying autoimmunological mechanism. The core of MCTD is an appearance of symptoms of several other inflammatory diseases of connective tissue – systemic lupus erythematosus, systemic scleroderma...
Mixed connective tissue disease)Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia. Related to Mixed connective tissue disease: polymyositis, Undifferentiated Connective Tissue Diseasedis·ease (dĭ-zēz′) n. 1. An abnormal condition of a part, organ, or system of an organism ...
Purpose: To report an unusualcase of retinal microvasculopathy secondary to mixed connective tissue disease(MCTD) on a background history of fragile-X syndrome (FXS). Methods: Case report and literaturereview. Results: A cotton wool spotwas discovere...关键词: Retinal Microvasculopathy Mixed Conn...