Response was assessed in all disease types. Clinical benefit response (CBR; composite of hemoglobin, fatigue, anorexia, fever/night sweats, weight, largest lymph node size) was also evaluated in Castleman disease.Sixty-seven patients received a median of 16 siltuximab doses for a median of 8.5 ...
Background and overview: The authors report the case of a patient with mixed connective tissue disease (MCTD) and Sjgren syndrome, showing signs and symptoms of bilateral trigeminal neuropathy and aseptic meningitis. The patient was assessed by means of quantitative sensory testing (QST) according ...
A 54-year-old woman who had been treated for mixed connective tissue disease for 4 years developed spontaneous rupture of extensor tendons in the wrist. The patient was surgically treated by tendon reconstruction. Histopathological examination of the synovial membrane showed lymphocytic inflammatory ...
Membranous glomerulonephritis in a patient with anti-u1 ribonucleoprotein (RNP) antibody-positive mixed connective tissue disease: A case reportWe report a 33-year-old Japanese man diagnosed with mixed connective tissue disease (MCTD) who developed nephrotic proteinuria. Both speckled antinuclear antibody...
A case of phosphaturic mesenchymal tumour (mixed connective tissue variant) that developed in the subcutaneous tissue of a patient with oncogenic osteomala... Phosphaturic mesenchymal tumor, mixed connective tissue type (PMTMCT) is a rare neoplasm that can cause tumor-induced osteomalacia due to ov...
Cranial vault shape, herein defined as the outer head surface encompassing the supraorbital ridge and extending towards the occipital bone, was extracted from structural MRIs (Supplementary Fig.1; Methods). Since the outer soft-tissue layer in this region is thin and uniform31, shape variation asso...
Anecdotal reports of CG in patients with mixed connective tissue disease (MCTD) have been reported in the literature. We report a case of a 53-year-old female who presented to us with acute kidney injury and proteinuria. The patient underwent renal biopsy for further evaluation of her ...
Mixed connective tissue disease (MCTD)PanniculitisA 51-year-old woman who had been suffering from mixed connective tissue disease (MCTD) for 8 years developed an erythematous rash with pain and tenderness on her left leg. A skin biopsy rev...Masahiro Nakashima...
1|TEXT I present a case of lingual Raynaud's phenomenon(RP)in a 37-year-old Caucasian woman followed for mixed connective tissue disease(MCTD).During scheduled follow-up,she shared a selfie photograph demonstrating RP of the tongue with deep blue/violet discoloration.She was asymptomatic and ...
A 23-year-old black woman with mixed connective tissue disease developed acute onset of shortness of breath and evidence of pulmonary edema. Cardiac isoenzymes, electrocardiograms and radionuclide myocardial scintigraphy were consistent with focal myocardial necrosis. The patient has had no further ...