包括癌症、心血管疾病、代谢疾病、糖尿病和病毒发病机制在内的疾病,以及miRNA失调作为疾病进展的一个因果因素已得到证实(Paul等人,2018)。然而,尽管试图发现特异性循环miRNA作为许多类型疾病(尤其是癌症)的诊断、预后和预测生物标志物,但它们尚未转化为临床成功(Jamali等人,2018;Salehi&Sharifi,2018)。 5. |心血管疾病...
In addition, a deletion of 1p21.3 containing a miRNA MIR137 has recently been reported by Willemsen et al. [19], and resulted in downregulation of the miRNA, and upregulation of three targets in subjects with ID and congenital abnormalities. Considering the role of MIR137 and its targets in...
Abdul-Careem M, Haq K, Shanmuganathan S, Read L, Schat K, Heidari M, Sharif S. 2009. Induction of innate host responses in the lungs of chickens following infection with a very virulent strain of Marek’s disease virus.Virology. 393(2):250–257. ...
ArticlePubMedPubMed CentralGoogle Scholar Raza A, Charagh S, Karikari B, Sharif R, Yadav V, Mubarik MS, Habib M, Zhuang Y, Zhang C, Chen H, Varshney RK, Zhuang W (2023) MiRNAs for crop improvement. Plant Physiol Biochem 201:107857 ArticlePubMedGoogle Scholar Reinhart BJ, Weinstein EG,...
Colorectal cancer (CRC) is the third highest frequent malignancy and ultimate critical source of cancer-associated mortality around the world. Regardless o
Alipoor B, Meshkani R, Ghaedi H, Sharifi Z, Panahi G, Golmohammadi T. Association of miR-146a rs2910164 and miR-149 rs2292832 Variants with Susceptibility to Type 2 Diabetes. Clin Lab. 2016;62(8):1553–1561. doi:10.7754/Clin.Lab.2016.160124 (Open in a new window)PubMed (Open in...
et al. Structural analysis and anti-tumor activity comparison of polysaccharides from Astragalus. Carbohydrate Polymers. 85, 895–902 (2011). Article CAS Google Scholar Chen, Y. et al. The anti-DHAV activities of Astragalus polysaccharide and its sulfate compared with those of BSRPS and its ...
Sharifi, H. et al. Micrornas and response to therapy in leukemia. J. Cell. Biochem. 120, 14233–14246. https://doi.org/10.1002/jcb.28892 (2019). Article PubMed CAS Google Scholar Li, Y. et al. Mir-339-5p inhibits metastasis of non-small cell lung cancer by regulating the epithel...
MicroRNAs (miRNAs) have critical roles in regulating cancer cell survival, proliferation and sensitivity to chemotherapy. The potential application of using miRNAs to predict chemotherapeutic response to cancer treatment is highly promising. However, the underlying mechanisms of chemotherapy response control ...
Toll-like receptors have gathered an extraordinary amount of interest in cancer research due to their role in the tumor progression86, where its activation has been linked to both cancer inhibition and growth. Yang et al.87reported that ten TLRs were expressed in MDA-MB-231 cells, and TLR-4...