related gene Western blot analysis showed that,the expression of CyclinE,CDK2, PCNA,UBC9 and K5 gradually increased after balloon injury which consisted with the neointimal hyperplasia. 3The expression of miR.29a increases in the intimal hyperplasia Real.time PCR results showed that the expression ...
Overall, present study also provides indications that that more intensive gene therapies and fibrosis level evaluations are needed for the management of chronic fibrosis patients. Experimental section Diabetic animal models Briefly, intraperitoneally administered the 50 mg/kg of streptozotocin (STZ) to the...
Our result reveals for the first time that inhibiting elevated microRNAs may be a more effective therapeutic approach than gene transfer to improve blood flow and muscle function in type 2 DM and PAD.doi:10.1210/jendso/bvaa046.2211Victor Lamin...
Gene polymorphismMicroRNAs, miR29aRecurrent spontaneous abortion (RSA) is a multifactorial disorder, and multiple genetic and environmental factors affect its pathogenesis. Recently, microRNA polymorphisms have been significantly associated with RSA incidence. This study aimed to evaluate the impact of miR2...
MiRNAs are a class of small, non-coding, single-stranded RNAs that regulate gene expression primarily through transcriptional repression of mRNA. We showed miR29a modulates ADAM12 expression in the setting of type 1 DM and ischemia. However, how miR29a modulates ADAM12 was not known. Moreover,...
Type of Aerobic Training Effect on Cardiac Muscles MIR29A and Collagen I Gene Expression in Diabetic Male Ratsiabetes is a very common disease in all countries and about a third of United States adults are pre diabetic (1). Exercise can reduce the blood glucose levels and leads to prevent ...
The Gene Expression Omnibus (GEO) dataset was used to corroborate the differential expression and diagnostic value of MIR29A . The bioinformatic identification were conducted to examine the interaction of MIR29A with LOX , LOXL2 , and VEGFA . The suppressive activity of MIR29A on LOX , LOXL2 ...
The Gene Expression Omnibus (GEO) dataset was used to corroborate the differential expression and diagnostic value of MIR29A. The bioinformatic identification were conducted to examine the interaction of MIR29A with LOX, LOXL2, and VEGFA. The suppressive activity of MIR29A on LOX, LOXL2, and ...
hsa-miR-29a-3p has been identified as a potential regulator of the Negative Regulatory Factor (Nef) gene from the HIV-1 viral genome. In this study, we aimed to compare the serum levels of hsa-miR-29a-3p with HIV-1 viral load in a substantial number of infected individuals. We ...