Expression and Correlation of miR-135a-5p, GATA3 and STAT3 in Cervical Cancer ZHANG Meng1, MA Dong2, YUAN Teng3, FAN Shaobei1, GUO Ying1, LIU Jia1, LI Ou4 1. Graduate School of North China University of Science and Technology, Tangshan 063210,China;...
miR-135A Regulates Preimplantation Embryo Development through Down-Regulation of E3 Ubiquitin Ligase Seven in Absentia Homolog 1A (SIAH1A) Expression. Yeung WS: miR- 135A regulates preimplantation embryo development through down- regulation of E3 Ubiquitin Ligase Seven In Absentia Homolog 1A (SIAH1A...
本发明涉及生物技术领域,具体涉及miR-135的用途及其相关药物.本发明首次揭示了miR-135与足细胞损伤的相关性,并首次揭示了过表达miR-135能够足细胞发生损伤,更类似于人类的发病过程.本发明的足细胞损伤模型具有足细胞损伤的典型特征,可极好地模拟体内足细胞损伤的发生发展,是足细胞损伤基础和临床应用研究的理想模型,从而...
目的:探讨miR-135 b、miR-141在结肠癌中的表达以及与肿瘤临床特征之间的相关性。方法分析2013年2月—2014年5月在上海市闸北区市北医院普通外科接受手术治疗切除的结肠癌及正常结肠组织标本。比较结肠癌与正常结肠组织的miR-135 b、miR-141表达差异,并探讨在结肠癌中miR-135b、miR-141的表达与其临床特征的相关性。
Inhibition of miR-33-5p and miR-135b-5p expression protected Neuro-2a cells from OGD-induced apoptosis. Inhibition of these two miRNAs significantly increased mRNA and protein levels of ATP-binding cassette subfamily A member 1 (ABCA1), and a binding assay showed that these two miRNAs showed ...
Inhibition of miR-33-5p and miR-135b-5p expression protected Neuro-2a cells from OGD-induced apoptosis. Inhibition of these two miRNAs significantly increased mRNA and protein levels of ATP-binding cassette subfamily A member 1 (ABCA1), and a binding assay showed that these two miRNAs showed ...