MCE 国际站:mmu-miR-15a-3p agomir 产品活性:mmu-miR-15a-3p agomir 是一种经过特殊化学修饰的miRNA模拟物,miRNA成熟链全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA agomir 可以模拟内源性miRNA,上调miRNA活性。与普通模拟物相比,miRNA agomir在动物...
目的:探讨miR-15a-3p通过调节碱性螺旋环螺旋转录因子1(Twist1)/Jagged1/Notch/Kruppel样因子4(KLF4)信号通路对肺腺癌细胞增殖,凋亡,迁移和侵袭的影响.方法:采用RT-qPCR实验检测肺腺癌组织,癌旁组织和肺腺癌细胞系(A549,HCC827)及人肺正常上皮细胞(BEAS-2B)中miR-15a-3p和Twist1 mRNA水平.A549细胞分成Cont...
产品活性:mmu-miR-15a-3p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA 相关产品:hsa-miR-4728-3p agomir | hsa-miR-126-3p agomir | rno-miR-6323 antagomir | mmu-miR-6395 inhibitor | hsa-miR-...
cgr-miR-15a-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:cgr-miR-15a-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:cgr-miR-15a-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
综上所述,miR-590-3p在CRC患者血浆外泌体中高表达且预示肿瘤恶性进展和不良预后,miR-590-3p具有成为CRC预后评估生物标志物的潜力。但本研究纳入样本量仍较少,且未囊括所有分期,因此血浆外泌体miR-590-3p在CRC中的作用以及通过调控下游哪些靶基...
Moreover, SLC39A7 was a direct downstream target of miR-15a-3p. Furthermore, SLC39A7 overexpression attenuated the effects of miR-15a-3p on cell proliferation, invasion, Wnt/beta-catenin pathway and EMT molecules. Conclusions: In summary, our study indicated that miR-15a-3p inhibited the ...
货号:tgu-miR-15a-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:tgu-miR-15a-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转...
The impact of miR-15a-3p on ovarian cancer cell growth, migration and invasion was measured by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT), wound-healing and transwell invasion assays. Bioinformatics and luciferase reporter assays were applied to identify that ...
Molecular cloning, characterization and expression of miR-15a-3p and miR-15b-3p in dairy cattle[J] . Zhixiong Li,Huilin Zhang,Ning Song,Hongliang Wang,Ling Chen,Mengxing Zhai,Xiaolin Liu.Molecular and Cellular Probes . 2014Li, Z. X., Zhang, H. L., Song, N., Wang, H. L., Chen, ...