miR-769-5p细胞凋亡细胞增殖目的探究miR-769-5p在皮肤黑素瘤(malignantmelanoma;MM)中的表达;以及其对人黑素瘤A375,G361细胞增殖的影响;以期为疾病的临床治疗提供新思路;方法收集本院保存的62例MM患者肿瘤组织以及对应癌旁组织进行研究;实时定量PCR(qRT-PCR)检测组织中miR-769-5p的表达;分析miR-769-5p表达与患者...
There are comments on PubPeer for publication: miR-769-5p suppressed cell proliferation, migration and invasion by targeting TGFBR1 in non-small cell lung carcinoma (2017)
货号:mml-miR-769-5p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mml-miR-769-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
(Thermo Fisher Scientific, Inc.; cat. no. 4366596) according to the manufacturer's protocol. The expression levels of miR-769-5p were assessed in triplicate using TaqMan probes for miR-769-5p (Thermo Fisher Scientific, Inc.; cat. no. 4427975; assay ID 001998) and the internal standard ...
通过平板克隆,EdU,transwell实验或体内皮下瘤模型评估miR-769-5p/3p通过IGF1R对胃癌细胞体内外生物学行为的影响.4.通过网络数据库等筛选出miR-769的上游转录因子STAT3,利用双荧光素酶报告基因实验验证SAHA对STAT3转录活性的影响,采用双荧光素酶报告基因和ChIP实验验证STAT3与miR-769启动子区的结合.通过平板克隆,EdU,...
R-769-5p表达水平呈负相关(P<0.05).血清LncRNA MALAT1,mi R-769-5p及联合检测诊断慢性牙周炎的曲线下面积(AUC)分别为0.800,0.743和0.877;龈沟液LncRNA MALAT1,mi R-769-5p及联合检测诊断慢性牙周炎的AUC分别为0.786,0.849和0.891.结论:慢性牙周炎患者血清和龈沟液LncRNA MALAT1表达水平升高,mi R-769-5p...
Figure 4.The effect of circ_0001955 on the proliferation and apoptosis of NSCLC cells by repressing miR-769-5p. P< 0.01, ***P< 0.001. Display full size Display full size Data availability statement The data used to support the findings of this study are available from the corresponding autho...
2022年4月,孙苏亚研究员在《Journal of Clinical Investigation》杂志在线发表题名为"Aberrant miR-339-5p/neuronatin signaling causes prodromal neuronal calcium dyshomeostasis in mutant presenilin mice.”——miR-339-5p/neuronatin信号...
There are comments on PubPeer for publication: MiR-129-5p inhibits glioma cell progression in vitro and in vivo by targeting TGIF2 (2018)
同时探讨miR-135b-5p和miR-499a-3p通过MEF2C对内皮细胞和血管平滑肌细胞的增殖和迁移等细胞行为的作用。研究方法1、血清中miRNA的获取:收集5m1动脉粥样硬化患者外周血,加入促凝剂,分离血清。利用Trizol分离方法,获取血清中miRNA.2、测定动脉粥样硬化患者血清中miRNA的水平:利用引物设计软件设计miR-135b-5p和miR-499...