目的:探讨miR-671-5p靶向肿瘤坏死因子α诱导蛋白8(TNFAIP8)对胰腺癌细胞增殖和凋亡的影响.方法:实时荧光定量PCR(qRT-PCR)和免疫印迹检测20例胰腺癌组织和与其配对的癌旁正常组织miR-617-5p,TNFAIP8 mRNA和TNFAIP8表达水平,验证miR-671-5p和TNFAIP8的靶向调控关系.将体外培养胰腺癌细胞capan-1分为miR-NC组,...
chi-miR-671-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:chi-miR-671-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:chi-miR-671-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
Conclusion: Downregulation of miRNA-671-5p, miR-193b-5p and miR-1307-5p in pre-treatment biopsy samples is associated with poor outcome and shorter progression free survival and poor treatment response leading to refractory/relapse DLBCL, which needs confirmation in larger studies. [Display omitted...
本发明提供了一种检测人血清外泌体中miR6715p试剂的应用及骨质疏松检测试剂盒,其包括miR6715p的逆转录引物,荧光探针,PCR引物,还可以进一步包括内参逆转录引物及其荧光探针,PCR引物,此外该试剂盒进一步包括miR6715p的参考品和内参.该试剂盒使用双重荧光定量PCR的方法从微量(200μL)血清或血浆中检测外泌体miR6715p...
miR-671-5p colon cancer prognosis proliferation migration invasion Introduction Colon cancer is one of the most common gastrointestinal malignancies worldwide, with a high morbidity and mortality rate.1Although the incidence and mortality rates of colon cancer have been declining in the United States, ...
1F是荧光素酶报告基因分析显示,miR-138-5p的过表达抑制KDM6B mRNA的3 ' -UTR驱动的荧光素酶活性,但不抑制突变的同源3 ' -UTR驱动的荧光素酶活性。 Part2miR-138-5p介导癌细胞诱导的巨噬细胞KDM6B表达抑制 2A是用miR-138-5p模拟...
The expression of TRIM14 was suppressed by miR-671-5p in papillary thyroid carcinoma. Overexpression of TRIM14 increased cell viability, and promoted the proliferation, migration, and invasion of papillary thyroid carcinoma. Moreover, TRIM14 counteracted the suppressive effect of miR-671-5p ...
Overexpressed miR-671-5p can suppress OS cell proliferation in vivo and in vitro, by the way of arresting cell-cycle progression. The overexpression of cyclin D1 (CCND1) and CDC34 promotes cell proliferation and cell-cycle promotion, whose functions are contrary to miR-671-5p. ...
miR-671-5pOsteoarthritisTCF4To explore the function of circular RNA IQ motif‐containing GTPase‐activating protein 1 (circ‐IQGAP1) in interleukin (IL)‐1β‐induced osteoarthritis (OA) model and to explore whether circ‐IQGAP1 can modulate microRNA‐671‐5p (miR‐671‐5p) and transcription ...
miR-671-5p agomir, pcDNA3.1-NF-κB, and negative vectors were administered into MCAO/R mice via intracerebroventricular injection. The results showed that miR-671-5p was significantly downregulated and that miR-671-5p agomir alleviated injury and neuroinflammation induced by ischemic reperfusion. A ...