mir-330-3p在制备治疗心肌梗死药物中的应用例如可以是:(1)使用mir-330-3p或过表达其的外泌体作为药物组分进行药物制备;(2)mir-330-3p作为药物作用靶点开发与其相关的心肌细胞铁死亡;(3)mir-330-3p作为药效评估因子,用于药物开发时评估治疗心肌梗死药物的药效等。 2、本发明的技术方案如下: 3、本发明一方面提供mi...
Moreover, we found that miR‐330‐3p interacted with phosphoglycerate mutase family member 5 (PGAM5) to regulate mitophagy. In specific, an overexpression of miR‐330‐3p diminished PGAM5 levels, which promoted mitophagy in response to IRI. In contrast, a downregulation of miR‐330‐3p was ...
miR-330-3p、FAM83H、LncRNA SNHG7在食管鳞癌组织中的表达及相关性研究 论㊀㊀著 m i R Ｇ３３０Ｇ３p ㊁F AM ８３H ㊁L n c R N AS N H G ７在食管鳞癌组织中的表达及相关性研究∗ 赵㊀静１,李㊀良１,郏莉莉２ １．东南大学附属中大医院江北院区/南京市大厂医院,江苏南京２１０...
货号:mml-miR-330-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mml-miR-330-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
本文探讨miRNA在NSCLC脑转移患者血中的表达特征,并进一步在体内,外实验中研究其对肺腺癌细胞生物学功能的影响,以及在表观遗传学中的调节和相关机制的研究.经研究,miR-330-3p在BM患者和肺腺癌细胞系上表达上调,沉默miR-330-3p的表达能够抑制肺腺癌细胞增殖,诱导细胞凋亡以及阻滞细胞周期,伴随凋亡相关蛋白,周期调控蛋白...
MicroRNAs (miRs) are involved in the regulation of many processes that contribute to malignancy, including cell proliferation, radiation resistance, invasion and metastasis. The role of miR-330-3p, an miR upregulated in breast cancer, remains unclear. We
circ_0003221靶向调控miR-330-3p.干扰circ_0003221或过表达miR-330-3p,U2-OS增殖抑制率升高,克隆形成数和迁移细胞数减少,划痕愈合率降低(P<0.05).抑制miR-330-3p表达可逆转干扰circ_0003221对U2-OS细胞增殖和迁移的影响.结论circ_0003221再骨肉瘤组织中高表达,干扰circ_0003221可通过上调miR-330-3p抑制骨肉瘤细胞...
miR-330-3pnon-small-cell lung cancerqRT-PCRRASSF1AObjectives This study was designed to investigate the role of circ_0078767/miR0/RASSF1A in non﹕mallヽell lung cancer (NSCLC). Bioinformatic analysis was performed to screen for the differentially expressed genes in NSCLC tissues from adjacent ...
qRT-PCR结果显示CRC临床标本癌组织中miR-330-3p的表达水平明显低于正常结直肠组织(P<0.01);过表达miR-330-3p的H T-29细胞中RU VBL1的表达明显下调,细胞内促凋亡蛋白Bax、cleaved-Caspase-3的蛋白表达水平均上调,而Bcl-2表达水平下降;过表达miR-330-3p的HT-29细胞凋亡增加,且对...
in prostate cancer 24 - Upregulation of microRNAs miR-9*, miR-330-3p and miR-345 in prostate cancer24 - Upregulation of microRNAs miR-9*, miR-330-3p and miR-345 in prostate cancerdoi:10.1016/S1569-9056(16)30165-8SDOSEuropean Urology Supplements...