miR-320dSTAT3MicroRNAs (miRNAs) play a key role in various pathological processes like atrial fibrillation (AF), which is a common cardiac arrhythmia. Exosomes are essential information carrier in the intercellular communication. Therefore, this study aimed to investigate the effects of exosomal miR-...
prognosisserum exosomeMicroRNAs (miRNAs) is a class of functional regulator of tumorigenesis of human cancer including hepatocellular carcinoma (HCC). However, the potential clinical significance of serum exosomal miR‐320d in HCC has not been elucidated....
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miRNAMIR-320dKIF3C雄激素剥夺治疗发病机制研究背景 近年来流行病学统计证实,男性前列腺癌特异性死亡占男性恶性肿瘤死亡第二位.由于前列腺癌特异性抗原(PSA)筛查的普及,越来越多的前列腺癌患者可以早期发现并接受及时的医疗治疗.虽然早期前列腺癌可以根治,但仍有约10%至20%的初诊前列腺癌患者进展为无法行手术根治的晚期...
We showed that miR-320d is increased in bronchial biopsies from COPD patients upon corticosteroid treatment and is negatively correlated with pro-inflammatory gene expression (Faiz et al. Eur Respir J 2019). We hypothesize that miR-320d has an anti-inflammatory role in airway epithelium. Our ...
miRNA-320d预后目的 探讨miR-320d表达与弥漫大B细胞淋巴瘤(DLBCL)预后的关系.方法 应用EnVision法对山西省肿瘤医院有随访资料的原发于淋巴结的DLBCL 62例石蜡标本进行CD20,CD3,CD10,bcl-6,Mum-1免疫标记检测,根据Hans分类方法将DLBCL分为生发中心B细胞(GCB)型和非生发中心B细胞(non-GCB)型.采用安捷伦16.0高密度...
By targeting GNAI1, miR-320d in these exosomes reduces GNAI1 levels in endothelial cells, causing more JAK2/STAT3 activation and VEGFA production. This ultimately enhances the migration and angiogenic capacity of vascular endothelial cells. Moreover, CRC patients with high levels of miR-320d in...
MiR-320dschizophreniaSchizophrenia is a chronic brain disorder and needs objective diagnostic biomarkers. MicroRNAs are highly expressed in the nervous system. The study investigated the expression and clinical values of serum miR-320d in schizophrenia patients. In addition, the underlying mechanism was ...
miR-320d can target and regulate c-Myc. Interference with c-Myc could reverse the increase in cell viability and ABCG2 expression caused by down-regulation of miR-320d. In conclusion, the combined chemotherapy with MR can enhance the chemotherapeutic sensitivity of CRC-SCs by up-regulation of...
AS1及miR-320d对SOX4表达的影响.结果 在C33A细胞中,miR-320d表达明显降低,HNF1A-AS1和SOX4表达明显升高,上调miR-320d抑制C33A细胞的增殖和EMT,促进癌细胞凋亡.HNF1A-AS13'UTR靶向miR-320d,敲低HNF1A-AS1抑制了C33A细胞增殖和EMT,促进癌细胞凋亡.下调HNF1A-AS1和miR-320d表达能部分逆转miR-320d下调对C33A细胞...