Using a luciferase expression system in OVCAR-3 cells, a miR-100 mimic repressed expression of SMARCA5 3′UTR by 40 % (p<0.0001), and FRAP1 3′UTR by 30% (p<0.0005). No effect of the mimic was observed when the predicted miR-100 binding sites in each gene's 3′UTR were mutated...