miR-23对FIS1表达的调控作用 2A. 荧光素酶报告系统检测miR-23和FIS1之间的相互作用;2B. 定量PCR检测miR-23对FIS1表达的调控 肾小管上皮细胞炎症因子表达检测 3A.miR-23水平对肾小管上皮细胞炎症因子表达的影响;3B.FIS1对肾小管上皮细胞炎症因子表达的影响;3C.miR-23通过FIS1对肾小管上皮细胞炎症因子表达...
血清m i R-124㊁m i R-155联合m i R-23检测 在超早期脑梗死诊断中的应用价值* 张立娜1,王海虹2,王适达3 河北省保定市第二中心医院:1.老年病科;2神经内2科;3.功能科,河北保定072750摘要:目的探究血清微小R N A(m i R)-124㊁m i R-155联合m i R-23检测在超早期脑梗死诊断中的应用价值㊂...
研究显示，miR-23a-3p在肝癌、前列腺癌中表达上调，具有促进癌细胞增殖、分化和抗凋亡作用［5-6］。研究显示，miR-29a在乳腺癌、卵巢癌中表达上调，具有促进乳腺癌细胞增殖、迁移、侵袭作用［7-8］。但关于二者在肾癌中作用的报道较少。本研究观察了肾癌患者血清miR-23a-3p、miR-29a表达变化，探讨其与临床病理特征...
目的研究微小RNA(miR)-23家族在脂多糖(LPS)诱导的人肾小管上皮HK-2细胞损伤中的作用及机制.方法培养人肾小管上皮HK-2细胞,将细胞分为对照组(给予不含药物的培养液),LPS组(给予含1 mg/L LPS的培养液),LPS+miR-NC组(转染NC模拟物6 h后更换为含有1mg/L LPS的培养液),LPS+miR-23a组(转染miR-23a模拟物...
Purpose. To investigate whether ADSC-derived miR-23-enriched exosomes could protect against calcium oxalate stone formation in a hyperoxaluria rat model. Methods. An ethylene glycol- (EG-) induced hyperoxaluria rat model and an in vitro mod
Figure 2. Enforced expression of the miR-23 family in T cells resulted in dysregulated T cell activation and cytokine production in mice. (A-E) Cellularity of the thymus and spleen and the proportions and absolute numbers of thymic and splenic total CD4+ T cells and Foxp3+CD4+ T reg...
www.nature.com/scientificreports OPEN MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation Received: 4 January 2017 Accepted: 28 June 2017 Published: xx xx xxxx Neri Mercatelli1, Simona Fittipaldi1,4, Elisa De Paola1,2, Ivan Dimauro 1, Maria Paola Paronetto1,...
目的 探究血清微小RNA(miR)-124、miR-155联合miR-23检测在超早期脑梗死诊断中的应用价值.方法 选取2018年2月至2019年2月在该院接受超早期脑梗死治疗的患者91例作为脑梗死组;另选同期在该院接受健康体检的体检健康者91例作为体检健康组.观察患者脑梗死体积、神经缺损程度、动脉粥样硬化(CAS)斑块性...
miR-23-27-24 endothelial cells cell-cell junctions miR-23 Introduction The sustenance of normal vascular permeability is one of the chief functions of endothelial cells (ECs) and is achieved mainly by the regulation of tightness of endothelial cell–cell junctions. Junctional integrity is maintained...
天津医科大学硕士学位论文 PPP2R5E的表达,实时定量PCR结果显示胃腺癌组织中miR-23a较癌旁组织表 达上调,而IRFl和PPP2R5EmRNA水平表..