(P<0.05);GSK-3β是miR-212-3p的靶基因,且过表达miR-212-3p的RA-SF中GSK-3β蛋白表达降低(P<0.05);敲减miR-212-3p降低了敲减NR2F1-AS1对RA-SF活性,凋亡及PCNA,cleaved-Caspase-3蛋白表达的影响.该研究提示,NR2F1-AS1可能通过靶向调控miR-212-3p/GSK-3β轴促进RA-SF增殖并阻碍其凋亡,其可能成为RA...
miR-212-3p regulates senescence of bone marrow mesenchymal stem cells by targeting MAPK3 Zhong Liying, Li Shundong, Wang Cong 中国组织工程研究 . 2025, (13): 2690 -2697 . DOI: 10.12307/2025.039 栏目设置More 种子细胞:培养与移植 生物材料:选择及转化 组织构建:方法和技术 临床应用:骨科植入物与...
Moreover, miR-212-3p directly bound to 3′UTR of SGK3 and inhibited its mRNA and protein expression. And over-expression of SGK3 rescued the decreased proliferation of GBM cells induced by miR-212-3p. Importantly, miR-212-3p also suppressed tumor growth in vivo. Collectively, our results ...
MCE 国际站:mmu-miR-212-3p agomir 产品活性:mmu-miR-212-3p agomir 是一种经过特殊化学修饰的miRNA模拟物,miRNA成熟链全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA agomir 可以模拟内源性miRNA,上调miRNA活性。与普通模拟物相比,miRNA agomir在动物...
miRNA ID: hsa-miR-212-3p Sanger Database NACRES: NA.55 Pricing and availability is not currently available.Recommended Products Slide 1 of 10 Sigma-Aldrich MIRAP00265 MystiCq® microRNA qPCR Assay Primer View Price and Availability Sigma-Aldrich MIRAP00266 MystiCq® microRNA qPCR Assay Prim...
miR-212-3pAXIN1Long non-coding RNA (lncRNA) nuclear-enriched assembly transcript 1 (NEAT1) has been reported to be highly expressed in Parkinson's disease (PD). However, the mechanism of NEAT1 in PD progression has not been fully elucidated. 1-methyl-4-phenyl-1, 2, 3, 6-...
代表什么意思？这种表示方法代表的意思是 3个miRNA 序列（miR-132, miR-212, miR-212-3p）具有共...
背景:骨质疏松症患者的骨髓间充质干细胞表现出明显衰老状态,并且细胞活性及成骨分化水平显著降低.miR-212-3p能够抑制人骨髓间充质干细胞的成骨分化,但其对骨髓间充质干细胞衰老调控的作用及机制尚不明确.目的:研究miR-212-3p通过靶向丝裂原活化蛋白激酶3(mitogen-activated protein kinase 3,MAPK3)对骨髓间充质...
摘要 目的探究circMAN1A2靶向miR-212-3p/DNA损伤诱导转录子4(NDA damage-inducible transcript 4,DDIT4)轴对胃癌细胞增殖、侵袭和迁移的影响。方法qRT-PCR法检测胃...展开更多 Objective To investigate the impact of circMAN1A2 on the proliferation,invasion and migration of gas-tric cancer cells by ...
货号:mml-miR-212-3p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:mml-miR-212-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...