Its low expression level was associated with increased tumour size, invasive depth, tumour node metastasis staging and lymph node metastasis, whereas high expression of miR 197 inhibited tumour cell proliferation and invasion in vitro. References to miR-197-3p ...
Mechanistically, circβ-catenin served as miRNA decoy to directly bind to miR-197-3p, then antagonized the repression of the target gene CTNND1, and eventually promoted the malignant phenotype of CRC. More interestingly, the inverted repeated Alu pairs termed AluJb1/2 and AluY facilitated the ...
miR-197-3p和miR-361-3p是两种被广泛研究的miRNA,其在肺癌中的表达水平与肿瘤的恶性程度和患者预后相关。研究表明,miR-197-3p的表达水平在肺癌组织中显著上调,与淋巴结转移、肿瘤分期和预后不良相关。miR-361-3p的表达水平在肺癌中也呈现出上调的趋势,并与患者的生存期明显相关。
产品编号: SF-1299 查看说明书 产品名称: miR-197-3p Hu-Cy3 SmartFlare Probe .0 订购此产品 供应商: Millipore 规格: EA 目录价: 9056 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址: 点击查看详细 打印此页 关闭此页 上一个:Anti-ACSL1[ABS606/EA] 下一个:...
miR-197-3p;SPOPL;osteosarcoma;cancer stem cells;stemness;chemoresistance Graphical Abstract 1. Introduction The most prevalent primary bone malignancy, osteosarcoma, affects children and adolescents primarily and accounts for one-third of all bone sarcomas. The standard practice for osteosarcoma includes pr...
货号:mml-miR-197-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mml-miR-197-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
Furthermore, we confirmed that miR-197-3p suppressed tumor xenograft growth invivo. In conclusion, our study offers an empirical investigation of miR-197-3p, a tumor suppressor that may be a potential therapeutic target in PCa. 展开 关键词: AKT VDAC1 miR-197-3p prostate cancer ...
Moreover, LIFR-AS1 was observed to up-regulate suppressor of fused gene (Sufu) expression by competitively binding to miR-197-3p in breast cancer cells. Notably, miR-197-3p inhibitor reversed the promoting effects of LIFR-AS1 knockdown on breast cancer cell proliferation, colony formation, ...
目的探讨水飞蓟素(SM)对胶质瘤细胞恶性生长的影响以及对miR-124-3p/WEE1轴的调控机制.方法将胶质瘤U87细胞分为对照组,SM低,中,高浓度组,SM高浓度+miR-124-3p抑制剂组(SM高+miR-124-3p inhibitor组).采用CCK-8法检测细胞增殖活性,Transwell实验检测细胞迁移和侵袭能力,流式细胞术检测细胞周期变化,Western blot...
在线靶基因软件预测SCAMP1的靶基因可能是miR-197-3p,经双荧光素酶报告系统鉴定两者之间的靶向关系.在肝癌SNU-449细胞中分别把SCAMP1 siRNA,miR-197-3p inhibitor共转染,利用上述方法检测细胞增殖,克隆,侵袭,迁移能力.结果:肝癌组织中SCAMP1表达水平高于癌旁组织,肝癌细胞内SCAMP1表达水平高于正常肝细胞,差异均有统计...