miR-194-3pp120-cateninThe epicardium is integral to cardiac development and facilitates endogenous heart regeneration and repair. While miR-194-3p is associated with cellular migration and invasion, its impact on epicardial cells remains uncharted. In this work we use gain-of-function a...
摘要:目的研究miRNA-194-3p在TGF-β1诱导的乳腺癌MDA-MB-231细胞上皮间质转化(EMT)发生中的作用,探讨miR-194-3p抑制乳腺癌侵袭的机制。方法体外培养人乳腺癌细胞系MDA-MB-231,采用TGF-β1加入人乳腺癌细胞系MDA-MB-231细胞培养液中制备细胞模型,RT-PCR检测miR-194-3p在TGF-β1诱导前后的表达变化。采用miRNA...
货号:ola-miR-194-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:ola-miR-194-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
Objective To study the role of miRNA-194-3p in the occurrence of epithelial interstitial transformation(EMT) in TGF-β1 induced breast cancer mda-mb-231 cells, and explore the mechanism of miR-194-3p inhibiting the invasion of breast cancer. Methods The cell model was prepared by adding TGF...
miR-194-3p Represses the Progesterone Receptor and Decidualization in Eutopic Endometrium From Women With Endometriosis 喜欢 0 阅读量: 46 作者: Pei,Tianjiao,Liu,Chang,Tingting,Xiao,Li,Luo,Bin,Tan 摘要: Progesterone resistance in the eutopic endometrium ...
mmu-miR-194-1-3p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。更多产品详情查看:www.medchemexpress.cn/mmu-mir-194-1-3p-mimic.html mmu-miR-194-1-3p mimic | mmu-miR-194-1-3p 模拟物 | MedChemExpress (MCE), mmu-miR-194-1-...
本研究发现川芎嗪能通过调控miR-143-3p和miR-194-5p的表达来影响人脐静脉内皮细胞的骨架重构。这为理解川芎嗪在血管内皮细胞生理功能调节中的作用提供了新的视角。此外,这一发现也为心血管疾病的预防和治疗提供了新的思路和方向。未来,我们将进一步深入研究川芎嗪及其在调控内皮细胞骨架重构过程中的具体作用机制,以期为...
miR-194-3pHMGB1目的:研究LINC02532调控miR-194-3p/高迁移率族蛋白l(HMGBl)轴对人瘢痕疙瘩成纤维细胞(HKF)增殖和凋亡的影响.方法:RT-qPCR法分析瘢痕疙瘩组织,正常皮肤组织中LINC02532和miR-194-3p表达量.将HKF细胞分为si-NC组,si-LINC02532组,miR-NC组,miR-194-3p组,si-LINC02532+anti-miR-NC组和si-...
(P<0.001).ROC分析显示,miR-194-3p,miR-296-3p及AMH三项指标联合诊断PCOS的诊断价值最大(AUC=0.917,95%CI:0.855~0.976),其敏感度为96.5%,特异度为81.4%.相关分析显示,PCOS患者血清miR-194-3p,miR-296-3p表达水平与AMH均呈正相关(r值分别为0.807,0.863,P<0.001).结论 血清miR-194-3p,miR-296-3p及AMH...
(课题组命名为Lnc BGSF)是骨正相关Lnc RNA,主要位于细胞质,其表达与微重力暴露时间呈依赖性下调,且作为mi R-194-3p的分子海绵,调控OGN的表达;此外,ICA可以促进Lnc BGSF表达且使其核质发生改变,进而调控OGN的表达水平.结论模拟微重力环境下,ICA可能通过Lnc BGSF/miR-194-3p/OGN轴调控骨代谢和成骨细胞分化进程...