miR-152-3p 通过靶向 FGFR3 抑制血管生成:利用 Starbase 预测并通过双荧光素酶报告基因分析、qRT-PCR 和 Western blot 验证,发现 miR-152-3p 可靶向成纤维细胞生长因子受体 3(FGFR3),抑制其表达。过表达 miR-152-3p 可抑制 HUVECs 的增殖、管腔形成和迁移,促进细胞衰老,而转染 miR-152-3p 抑制剂则产生相反...
目的:探讨LncRNA SNHG4通过调节miR-152-3p对人牙周膜干细胞成骨分化的影响。方法:从因正畸需要而拔除的前磨牙牙周膜组织中分离出人牙周膜干细胞,将其进行成骨诱导分化0,7,14 d后,qRT-PCR检测Runt相关转录因子2、骨钙素、LncRNA SNHG4及m...
本研究基于实验室以往高通量测序结果分析,从不同年龄的小鼠胸腺和TECs测序结果中筛选出与年龄相关的差异上调的miRNAs共54个,选取其中一个miR-152-3p.以小鼠髓质胸腺上皮细胞系(medullarythymicepithelial cell line1,MTEC1)细胞为研究对象,通过CCK-8法,EdU掺入法,流式细胞术,实时荧光定量PCR,双荧光素酶报告基因实验...
在miR-152-3p模拟物+ pcDNA3.1-SLC2A1转染的U251细胞中SLC2A1表达增加。miR-152-3p模拟组显着抑制了U251细胞的增殖,迁移,侵袭和糖酵解,且增加凋亡。 6.LINC00174通过靶向miR-152-3p在神经胶质瘤中发挥肿瘤发生作用 为证实LIN...
There are comments on PubPeer for publication: miR-152-3p Sensitizes Glioblastoma Cells Towards Cisplatin Via Regulation Of SOS1 (2019)
年6月驻马店市中心医院收治的非小细胞肺癌患者105例,收集患者入院时的临床资料,采用实时荧光定量聚合酶链反应检测非小细胞肺癌患者肿瘤组织和癌旁组织中的miR-152-3p表达水平,比较肿瘤组织和癌旁组织中miR-152-3p的表达水平,比较不同临床特征患者miR-152-3p的表达水平,采用点二列相关性分析miR-152-3p表达水平与...
货号:mml-miR-152-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mml-miR-152-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
FOXF1 overexpression significantly inhibits cell proliferation, invasion, and extracellular matrix in keloid fibroblasts, and the suppressive effects of miR-152-3p mimic on these functions were notably partly reversed by FOXF1 overexpression. Taken together, these findings indicated that miR-152-3p ...
miR-152-3p;Smad2;thymic epithelial cells;cell proliferation 1. Introduction The thymus is an important immune organ both in animals and humans. It mainly comprises the thymocytes and thymic stromal cells at different stages of maturity. The thymic epithelial cells (TECs) constitute the thymic stroma...
Cancer Cell Int (2021) 21:440 https://doi.org/10.1186/s12935-021-02061-0 Cancer Cell International PRIMARY RESEARCH Open Access OIP5‑AS1 contributes to the development in endometrial carcinoma cells by targeting miR‑152‑3p to up‑regulate SLC7A5 Minglin Liang, Hongbo...