miR-130b-3pmiR-130b-5pKLF3肌内脂肪细胞分化肌内脂肪(Intramuscular fat,IMF)含量主要取决于肌内脂肪细胞的脂肪形成和成熟脂肪细胞脂质的积累.脂肪沉积主要由脂肪细胞增殖和分化的程度决定,而miRNA(micro RNA)是真核生物中发现的一类通过与特异的靶基因结合进而在基因转录后调控细胞分化的内源性非编码RNA.近年来,...
2022年7月20日,西安医学院临床医学院妇产科教研室相萌团队报道miR-130b-5p过表达可显著促进HTR8/SVneo细胞增殖抑制率和E-cadherin表达水平,降低c-Myc、CyclinD1表达水平、迁移距离、侵袭细胞数、MMP9、MMP2、N-cadherin、Vimentin表...
货号:cgr-miR-130b-5p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:cgr-miR-130b-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制...
The aim of the present study was to investigate the targeted interaction between microRNA (miR)-130b-5p and RAS protein activator like 1 (RASAL1) gene and elucidate the function of miR-130b-5p in cell proliferation, migration and invasion in gastric cancer. Expression of miR-130b-5p and ...
miR-130b-5p和miR-142-5p表达水平显著高于对照组(P均<0.05).多因素结果分析显示血清miR-130b-5p和miR-142-5p表达水平是影响高危型HPV阳性患者发生宫颈癌的独立危险因素(P<0.05).血清miR-130b-5p和miR-142-5p水平评估宫颈癌诊断AUC分别为0.737,0.746,联合检测AUC为0.833.结论血清miR-130b-5p和miR-142-5p...
In addition, the expression of RASAL1 was significantly lower in MGC803 cells that were transfected with miR-130b-5p mimics and significantly higher in cells transfected with miR-130b-5p inhibitor in comparison with cells transfected with NC (P < 0.05). Furthermore, the experimental group ...
外周血白细胞中miR-130b-5p在计算辐射剂量中的应用本发明提供外周血中白细胞miR130b5p在计算辐射剂量中的应用.本方法主要通过检测生物体外周血白细胞中miR130b5p在遭受辐射后表达量,代入剂量效应函数关系式,即可计算辐射量.本方法操作简单,方便快捷,客观.李佳迅...
【目的】探究微小RNA 130b-5p(miR-130b-5p)靶向胰岛素样生长因子-1(IGF-1)对人绒毛膜滋养层细胞(HTR8/SVneo)迁移及侵袭的影响.【方法】将HTR8/SVneo细胞分为对照组,miR-NC组,miR-130b-5pmimics组,miR-130b-5pmimics+pcDNA3.1组和miR-130b-5pmimics+pcDNA3.1-IGF-1组,双荧光素酶报告基因检测miR-130...
wound healingadipose-derived stem cellsexosomeE2F1miR-130b-5pBackground Skin wound is a widespread health problem and brings extraordinary burdens to patients. Exosomes derived from adipose-derived stem cells (ADSC-Exos) are considered promising strategies for repairing skin wounds. E...
Genes regulated by antitumor miR-130b-5p were closely involved in PDAC molecular pathogenesis. Our approach, discovery of antitumor miRNAs and their target RNAs, will contribute to exploring the causes of this malignant disease.doi:10.1038/s10038-019-0584-6Fukuhisa, Haruhi...