mmu-miR-128-1-5p mimic CAS No. : MCE 国际站:mmu-miR-128-1-5p mimic 产品活性:mmu-miR-128-1-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA 相关产品:hsa-miR-4728-3p agomir | hsa-miR...
中文名称:hsa-mir-128-1-5p RT-PCR反应引物 英文名称:hsa-mir-128-1-5p RT-PCR Primer Set 品牌:Abbexa 货号:abx096853 规格:1 nmol 价格: $246.5 产品说明书下载: 产品预定 >> 产品预定,提交订单信息之后,我们会第一时间与您取得联系 试剂和工具 ...
摘要: We first verified ADSC-Exosomal miR-128-1-5p can inhibit skin fibrosis.Our data revealed ADSC-Exos can inhibit TGF-β1 expression induced by high glucose.ADSC-Exos can decrease α-SMA and Col I through the miR-128-1-5p/TGF-β1/Smad axis.关键词:...
In this study, we tested whether miR-128 can also control L1 activity by repressing cellular proteins important for L1 retrotransposition. We found that miR-128 targets the 3′ UTR of nuclear import factor transportin 1 (TNPO1) mRNA. Manipulation of miR-128 and TNPO1 levels demonstrated ...
本研究拟在此基础上进一步证实Rap1B是miR-128、miR-149及miR-181的直接调控靶基因,并证实它们在不同WHO分化级别的星形胶质细胞瘤中的表达变化,进而阐明miR-128、miR-149及miR-181通过靶向Rap1B对脑胶质瘤细胞增殖和侵袭的影响以及增强替莫唑胺(temozolomide, TMZ)对脑胶质瘤细胞化疗敏感性的作用机制。 [Rap1B...
实验结果显示,在类风湿关节炎患者中NEAT1表达水平升高,而miR-128-3p和SIRT1表达水平降低。此外,研究还发现LncRNA NEAT1可以通过吸附miR-128-3p来抑制miR-128-3p的表达,从而增强SIRT1的表达,促进自噬进程。 4. 结论 本研究表明,LncRNA NEAT1/miR-128-3p/SIRT1通路在类风湿关节炎自噬调控过程中具有重要的作用。
Additionally, PCAT-1 functioned as a sponge of miR-128 in GC cells. Moreover, inhibition of miR-128 reversed the inductive effect of PCAT-1 knockdown on DDP sensitivity of GC cells. In addition, ZEB1 was identified as a target of miR-128, and overexpression of ZEB1 could block the ...
目的: 研究miR-128-3p通过靶向SIX1表达,调控线粒体功能从而改善上皮细胞损伤并延缓哮喘气道炎症. 方法: 体内实验:选用40只BALB/c小鼠作为研究对象,每组10只随机分为正常组(Con),模型组(OVA),模型组+agomir NC 组(OVA+agomir NC),模型组+miR-128-3p agomir 组(OVA+miR-128-3p agomir).观察指标:(1)小鼠...
We found that miR-128-2 might down-regulate a group of genes including BCL11a, MALT1, A2b et. al. to inhibit B cell development confirmed by luciferase assay, real time PCR and western blot. Thus, our present study suggests that miR-128-2 mainly blocks CLP to differentiate into PreProB...
International Journal of Molecular Sciences Article miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA Lianna Fung 1, Herlinda Guzman 1, Evgueni Sevrioukov 1, Adam Idica 1, Eddie Park 2, Aurore Bochnakian 1, Iben Daugaard 1, Douglas Jury 1, Ali ...