miR-30c-1-3p/miR-103a-2-5p overexpression could inhibit AR-V7 expression, suppress VCaP cell growth, and inhibit AR-V7 downstream factor expression by directly targeting the 3'-untranslated region of AR-V7. Under enzalutamide (Enza) treatment, the effects of AR-V7 overexpression were the ...
LncRNA LTSCCAT promotes tongue squamous cell carcinoma metastasis via targeting the miR-103a-2-5p/SMYD3/TWIST1 axis Mo Liu, Qingwen Liu, Song Fan, Feng Su, Chun Jiang, Guanming Cai, Youyuan Wang, Guiqing Liao, Xinyuan Lei, Weixiong Chen, Junming Bi, Weiqi Cheng, Luo...
In addition, overexpressed miR-103a-2-5p reduced both the relative expression of Nrf2/HO-1 pathway-related proteins and the ratio of GSH/ROS, leading to the excessive intracellular ROS that may promote AML cell apoptosis. In the mouse model, the delivery of miR-103a-2-5p through CLPs ...
In contrast, microRNA (miR)‐30c‐1‐3p/miR‐103a‐2‐5p expression was significantly downregulated in tumor tissues and cells. miR‐30c‐1‐3p/miR‐103a‐2‐5p overexpression could inhibit AR‐V7 expression, suppress VCaP cell growth, and inhibit AR‐V7 downstream factor expression by ...
Tumor-derived exosomal miR-103a-2-5p facilitates esophageal squamous cell carcinoma cell proliferation and migrationGAO, D.-C.HOU, B.ZHOU, D.LIU, Q.-X.ZHANG, K.LU, X.ZHANG, J.ZHENG, H.DAI, J.-G.European Review for Medical & Pharmacological Sciences...
The effect of pcDNA/LTSCCAT on expression was attenuated by miR-103a-2-5p mimics. The RF and SVM classifier predicts that LTSCCAT can bind to SMYD3, whereas the RNA immunoprecipitation (RIP) assay confirms that it cannot. In addition, we predicted the combination of LTSCCAT and SMYD3 ...