抑郁模型,模型大鼠,海马区,调控,MKP-1,行为学评估,microRNA,强迫游泳实验目的 用动物行为学,分子生物学与细胞生物学等技术方法,研究慢性不可预见性温和性应激(CUMS)所致的抑郁样行为与miR-101a-3p microRNA,MKP-1之间的关系,并初步明确miR-101a-3p microRNA通过调控MKP-1参与抑郁症发生的分子机制.方法 SD大鼠...
ola-miR-101a-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:ola-miR-101a-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:ola-miR-101a-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对...
C-FOS was a target of miR-101a-3p and miR-101a-3p negatively regulated c-FOS expression to function in epilepsy. Overexpression of miR-101a-3p attenuated pilocarpine-induced epilepsy in Rats in vivo. This study indicated that miR-101a-3p could attenuate pilocarpine-induced epilepsy by ...
After miR-101a-3p was overexpressed, the neurological function of PD mice was improved, and the apoptosis of Neuro-2a cells induced by MPP+ was alleviated, and the accumulation of 伪-synuclein protein was reduced; ROCK2 overexpression counteracted the protective effect of miR-101a-3p. ...
microRNA, miR-101a-3p, Ezh2, Polycomb Repressive Complex 2, Amygdala, AnxietyA greater understanding of neural mechanisms that contribute to anxiety is needed in order to develop better therapeutic interventions. The current study interrogates a novel molecular mechanism that shapes anxiety-like ...
In total, we therefore identified four microRNAs, namely miR-101a-3p, miR- 140-5p, miR-330-5p, and miR-376b-3p, which can regulate rat HspB5 directly or indirectly.BrittaBarteltKirbach · NikolaGolenhofen
In total, we therefore identified four microRNAs, namely miR-101a-3p, miR-140-5p, miR-330-5p, and miR-376b-3p, which can regulate rat HspB5 directly or indirectly.Britta,Bartelt-KirbachNikola,GolenhofenCell stress & chaperones