Berger, Relation of cerebral small-vessel disease and brain atrophy to mild Parkinsonism in the elderly, Mov. Disord. 21 (2006) 1914e1919.Reitz C, Trenkwalder C, Kretzschmar K, Roesler A, Eckardstein V, Berger K. Relation of cerebral small-vessel disease and brain atro- phy to mild ...
Imaging markers of small vessel disease (SVD) (white matter hyperintensities [WMH] on structural MRI, visual scores and volume; perivascular spaces; lacunes and microbleeds), and vascular risk measures were assessed in both cohorts. We assessed associations between retinal and brain measurements using...
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potent... magnetic resonance imagingneuropsychological testingsmall vessel pathologyThere is evidence that Alzheimer's disease (AD) has significant cerebrovascular...
We demonstrated a significant prevalence of small vessel markers of cerebrovascular pathology in individuals diagnosed with AD, with a significant concurrence between cerebrovascular disease and brain and ventricular atrophy. While current research on AD has focused on amyloid-βpeptide deposition, tau-...
Notably, profound myocardial injury or structural heart disease is not prerequisite for the presence of symptoms defying the classical definitions of viral myocarditis. Subclinical cardiovascular inflammation is increasingly recognized as a risk factor in chronic autoimmune systemic conditions, necessitating ...
The global burden of cerebral small vessel disease in low- and middle-income countries: a systematic review and meta-analysis[J]. Int J Stroke, 2023,18(1):15-27. [7] Bernbaum M, Menon BK, Fick G, et al. Reduced blood flow in normal white matter predicts development of leukoaraiosis...
Midlife systemic inflammation, late-life white matter integrity, and cerebral small vessel disease: the Atherosclerosis Risk in Communities study. Stroke. 2017;48(12):3196-3202. doi:10.1161/STROKEAHA.117.018675PubMedGoogle Scholar 17. Manly JJ, Glymour MM. What the aducanumab approval ...
In addition to neurodegenerative brain changes, dementia is frequently associated with vascular pathologies such as small vessel disease (multiple or single infarcts)38. EGb 761 extract has various beneficial properties, although its mechanism of action in cognitive disorders is not yet fully understood...
Ischemic brain lesions associated with hypertension (HTN). HTN induces atherosclerosis of major extracranial and intracranial arteries, which could lead to major infarcts. HTN causes both microbleeds and macrobleeds and is the main pathogenetic factor for small vessel disease responsible for lacunar ...
RationaleCerebral small vessel disease (SVD) is common in ageing and patients with dementia and stroke. Its manifestations on magnetic resonance imaging (MRI) include white matter hyperintensities, lacunes, microbleeds, perivascular spaces, small subcortical infarcts, and brain atrophy. Many studies focus...