Hippocampal subfield atrophyCerebral small vessel diseaseMild cognitive impairmentAlzheimer’s diseaseTo investigate patterns of hippocampal subfield atrophy among patients with amnestic mild cognitive impairment, stratified by severity of small vessel disease (SVD) and corresponding associations with cognitive ...
Presently, the pathogenesis of cerebral small vessel disease (SVD) in humans is not completely understood, in part due to the difficulty in imaging in vivo the cerebral microvasculature. SVD is a syndrome of cognitive, clinical, neuroimaging and neuropathological findings arising from disease affecti...
Small vessel cerebrovascular disease in older adults 'Cerebral small vessel disease' is common in older adults and is an important cause of morbidity, functional impairment and cognitive decline. Small vessel... H Slavin,J Mcmanus,DJ Stott - 《Reviews in Clinical Gerontology》 被引量: 10发表: ...
77vs. 69,P < 0.001), had a higher prevalence of hypertension (63.9%vs. 38.1%,P = 0.045) and were more likely to present with indications of cerebral small vessel disease (SVD), such as white matter hypersensitivity (WMH) (34.4%vs. 4.8%,P = 0.009), and impaired instrume...
Hypertension is the major modifiable risk factor for stroke and small vessel disease. It has been suggested that cerebral microvascular disease contributes to vascular cognitive impairment. The mechanisms underlying hypertension-related cognitive changes are complex and not yet fully understood. Both high ...
Objective To discuss the correlation of mild cognitive impairment and plasma homocysteine( Hcy) and highsensitivity C-reactive protein( hs-CRP) level in patients with cerebral small vessel disease. Methods From March 2015 to July 2015,100 cases of cerebral small vessel disease patients were collected...
Midlife systemic inflammation, late-life white matter integrity, and cerebral small vessel disease: the Atherosclerosis Risk in Communities study. Stroke. 2017;48(12):3196-3202. doi:10.1161/STROKEAHA.117.018675PubMedGoogle Scholar 17. Manly JJ, Glymour MM. What the aducanumab approval ...
Is cognitive function a determinant of exercise capacity in patients with coronary artery disease? In atherosclerotic patients, the presence of coronary microvascular dysfunction as determined by low coronary flow reserve is associated with abnormal cerebral ... D Saklica,N Vardar-Yagli,AH Ates,......
et al. Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model. Neuroscience. 408, 361–377. https://doi.org/10.1016/j.neuroscience.2019.04.018 (2019). Article CAS PubMed Google Scholar Madrigal, J. L., Leza, J. C., ...
The validity, reliability and clinical utility of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in patients with cerebral small vessel disease. Dementia and geriatric cognitive disorders 28, 81–87, https://doi.org/10.1159/000232589 (2009). Article PubMed Google Scholar Yeung, P. Y.,...