Exercise Attenuates Chronic Unpredictable Mild Stress Induced Brain Microvascular Rarefaction In Obese Zucker Rat: Role Of Stat3 SignalingSkeletal muscle arterioles from obese Zucker rats (OZR) exhibit oxidant stress-based alterations in reactivity, enhanced alpha-adrenergic constriction, and reduced ...
amygdala, parahippocampal, fusiform, inferior temporal, and middle temporal cortical regions; mean ± SD.bMean11C-PiB PET uptake in each group at baseline, two-year follow-up, and longitudinal change. The mean uptake was
1 However, the biological processes driving an acute biomechanical injury to a chronic, lifelong pathology associated with late neurodegenerative disease remain uncertain.2,3 Among TBI-related pathologies, vascular injury is recognized as a common pathology, with outcomes ranging from macrov...
Microvascular brain pathology and late-life motor impairment. Neurology. 2013;80(8):712-718.PubMedGoogle ScholarCrossref 61. Buchman AS, Yu L, Wilson RS, Boyle PA, Schneider JA, Bennett DA. Brain pathology contributes to simultaneous change in physical frailty and cognition in old age. J...
We investigated the relationship between BMI and the risk of progression to AD in subjects with MCI, as well as the effect of BMI on progression to AD depending on age, sex, cognitive intervention, and chronic diseases. Methods Three hundred and eighty-eight MCI subjects were followed for ...
In addition to the association of sleep and beta amyloid mentioned above, animal models showed that neuronal activity as observed during extended wakefulness or chronic sleep restriction could lead to an increase in tau production64,65,66. However, it is also difficult to identify the directionality...
(CONTEC Medical Systems Co., Ltd.; Shanghai, China).Exclusion Criteria: An unstable psychiatric condition; a need for change in current psychiatric medication prescriptions; suicidal ideations or suicide attempts at the time of recruitment; drug abuse; acute or chronic respiratory disease; any ...
whereas higher doses of caffeine may impair memory acquisition. Biological effects of caffeine on brain function also included modulation of white matter lesions and/or microvascular ischemic lesions, and improved insulin sensitivity, so reducing the risk of type 2 diabetes, which is a strong risk ...
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1 However, the biological processes driving an acute biomechanical injury to a chronic, lifelong pathology associated with late neurodegenerative disease remain uncertain.2,3 Among TBI-related pathologies, vascular injury is recognized as a common pathology, with outcomes ranging from macrova...