To stabilize the positional relationship between the nucleus and centriolar complex, while nuclear morphogenesis is taking place, a series of microtubules develop which emanate from the centriolar complex and extend to the nuclear envelope lining the fossa. Buttressing microtubules also develop within the...
1. microtubules emanate from these structures 2. surface for chemical reactions; part of the intracellular transport system, it has ribosomes attached for a protein synthesis 3. surface for chemical reactions; part of t How do cells sense chemoattractants/chemorepellants and also explain the ...
The interaction of Borealin with microtubules could regulate the amount of the CPC bound to the centromere, the transfer of the signal from the inner centromere to kinetochores or both of these steps. Note that the former is a complexity that was not included in our model and confounds the ...
Based on these results, we concluded that RNP-1 protects microtubules from nocodazole. Localization of RNP-1-GFP in dividing cells As microtubule structures are vital to cytokinesis and cell migration, we next assessed the role of RNP-1 in cytokinesis and cell migration. A plasmid encoding a C...
Here CRMP2 was present in mitotic structures and in puncta along the mitotic spindle at metaphase and on the midzone MTs in late telophase (Fig. 1B). Exogenous HA-tagged CRMP1 was similarly localized on the mitotic spindle and midzone MTs in these cells (data not shown). CRMP2 puncta ...
2a). However, confirmation that the filamentous structures at telomere attachment sites in the micrographs are indeed LINC complexes demands the molecular mapping of SUN1 and KASH5 to these filaments at higher resolution in structurally well preserved testis tissue. To this end, we performed pre-...