朱学娥,向芳,罗东,等. microRNA-27b、microRNA-221、microRNA-222和血管内皮生长因子在瘢痕疙瘩中的表达及相关性研究[J]. 中华整形外科杂志,2023,39(08):844-850.DOI:10.3760/cma.j.cn114453-20220808-00246 【摘要】 目的探讨瘢...
Among the 26 miRNAs, microRNA-222 (miR-222) was our research focus because its increased expression promoted neurite outgrowth while it silencing by miR-222 inhibitor reduced neurite outgrowth. Knockdown experiments confirmed that phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a ...
【摘要】目的 检测 microRNA-222(miRNA-222)在肝细胞癌(HCC)组织中的表达, 并探讨其临床意义.方法 收集 2012 年 1 月-2014 年 12 月于大连市中心医院、大 连医科大学附属第一医院手术切除的 HCC 组织 103 例,采用实时定量 PCR 方法检 测 HCC、近癌旁肝硬化组织及远癌旁肝组织中 miRNA-222 的表达水平,...
目的:探讨 microRNA(miR)-155和 miR-222在室间隔缺损(VSD)患者血浆中的表达变化及临床意义,对其可能的分子调控机制进行初步分析.方法选取2012年8月至2013年6月在济南市儿童医院心血管外科就诊和治疗的 VSD 患者20例(病例组),同期骨外科骨折患者15例(对照组).反转录实时定量PCR(RT-qPCR)测定各组研究对象血浆 mi...
Reconstitution of normal levels of Rbm24 in cells overexpressing microRNA-222 rescues muscle-specific splicing. In conclusion, we have identified a new function of microRNA-222 leading to alteration of myogenic differentiation at the level of alternative splicing, and we provide evidence that this ...
(2013) Exploration of genome-wide circulating microRNA in hepatocellular carcinoma: MiR-483-5p as a potential biomarker. Cancer Epidemiol Bio- markers Prev 22: 2364-2373. doi: 10.1158/1055-9965.EPI-13-0237 PMID: 24127413... S Jing,A Wang,W Qiao,... - 《Cancer Research》 被引量: 83发...
TargetingmicroRNAexpressiontoregulateangiogenesisAngelikaKuehbacher,CarmenUrbichandStefanieDimmelerMolecularCardiology,InternalMedicineIII,University..
The aim of the research was to examine the expression level of microRNA221/222 (miR-221/222) in the serum of patients with type 2 diabetes mellitus (T2DM) who are also diagnosed with post-menopausal breast cancer. We aimed to evaluate the differences in microRNA expression in patients with...
222表达水平明显高于非冠心组病患者,冠心病组患者microRNA-221 /222表达水平与内皮祖细胞的数量呈负相关,经阿托伐他汀干预6个月后,冠心病组患者内皮祖细胞的数量较基线时明显增加,而microRNA-221 /222水平显著降低.结论:阿托伐他汀可增加冠心病患者内皮祖细胞的数量以及降低冠心病患者内皮祖细胞中microRNA-221/222...