2021年12月27日,Clinical and Translational Discovery 杂志在线发表了天津南开大学Yiyao Jiang 教授团队的最新成果 “ MicroRNA-144-3p controls the apoptosis of pulmonary artery endothelial cells in pulmonary arterial hypertension v...
医学论文:MicroRNA-144靶向调控Nrf2在 糖尿病心肌病发展过程中的作用机制研究 第一部分MicroRNA在DCM心肌中的表达谱 一、前言 糖尿病(Diabetesmellitus,DM)是一种进展性代谢紊乱疾病,它 能最终导致包括肾衰、失明和心力衰竭等一系列慢性血管并发症的发 生[1]。糖尿病心肌病(Diabeticcardiomyopathy,DCM)是DM患者心 ...
转录因子GATA-I和EKLF可以结合在microRNA-144 ～ 451基因簇并激活microRNA-144或microRNA-451的表达;在K562细胞中过表达microRNA-144或microRNA-451均可促进hemin诱导的红系分化;另一方面,microRNA-144和microRNA-451可以通过抑制GATA-2的表达促进细胞向红系分化.结论 microRNA-144～ 451基因簇在红系分化过程中...
miR-144 was one of the differentially expressed miRNAs and showed a 5.59-fold change in pre-ovulatory ovarian follicles between LW and CT sows with Solexa deep sequencing technology. Therefore, miR-144 was selected as a candidate miRNA for analysis of ovulation. TargetScan and RNAhybrid were used...
As a key component of the RNA-induced silencing complex (RISC), Argonaute2 (Ago2) exhibits a dual function regulatory role in tumor progression. However, the mechanistic basis of differential regulation remains elusive. p63 is a homolog of the tumor supp
大鼠卵巢中microRNA-144表达,发现模型组中该表达显著下降,中药治疗后显著升高.WB测定AKT/mTOR,自噬相关蛋白,结果发现以上指标在模型组中的表达分别受到抑制和促进作用,中药治疗后,均有改善.结论补肾宁心汤对POI大鼠的卵巢功能有保护作用,可改善大鼠内分泌和减缓卵泡闭锁,起效的机制可能与上调microRNA144/AKT/mTOR通路...
To identify abnormal miRNAs critical for air pollution-related tumourigenesis, we performed microRNA microarray analysis in 6 Xuanwei non-small cell lung cancers (NSCLCs) and 4 NSCLCs from control regions where smoky coal was not used. We found 13 down-regulated and 2 up-regulated miRNAs in ...
et al. Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. J Nanobiotechnol 9, 40 (2011). https://doi.org/10.1186/1477-3155-9-40 Download citation Received13 June 2011 Accepted19 September 2011 ...
MicroRNA-144 represses gliomas progression and elevates susceptibility to Temozolomide by targeting CAV2 and FGF7 Zhi-Qin Liu, Jing-Jing Ren, Jun-Long Zhao, Jian Zang, Qian-Fa Long, Jing-Jing Du, Xiao-Tao Jia, Nai-Bing Gu, Zheng-Li Di, Yi-Hua Qian & San-Zhong Li ...
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