Microglial cells are tissue macrophages of the central nervous system, with important role in surveillance and in the clearance of dead cells and extracellular matrix. Despite their role in the homeostasis of the central nervous system, microglial cells have also been correlated to several pathological...
Microglial cells are a specialised population of macrophages that are found in the central nervous system (CNS). They remove damaged neurons and infections and are important for maintaining the health of the CNS. Latest Research and Reviews
(Medical Xpress)—In many pathologies of the nervous system, there is a common event - cells called microglia are activated from surveillant watchmen into fighters. Microglia are the immune cells of the nervous system, ingesting and destroying pathogens and damaged nerve cells. Until now little w...
Glial cells are a family of cells that perform highly specialized roles within the central nervous system of mammals. Microglia, astrocytes and oligodendrocytes are three major sub-types of this family. Microglia have recently been identified to play a central role in modulating synaptic structure, s...
3 Microglia in PD Microglia are the resident innate immune cells in the brain and have a role in monitoring the brain for immune insults and invading pathogens. Neurons may benefit from activated microglia because the latter were proposed to constantly move and to monitor the area in which they...
Role of the Cell Cycle in the Pathobiology of Central Nervous System Trauma Up-regulation of cell cycle proteins occurs in both mitotic and post-mitotic neural cells after central nervous system (CNS) injury in adult animals. In mi... I Cernak,BA Stoica,KR Byrnes,... - 《Cell Cycle》 被...
Microglia, the immune cells of the central nervous system, have long been a subject of study in the Alzheimer's disease (AD) field due to their dramatic responses to the pathophysiology of the disease. With several large-scale genetic studies in the past year implicating microglial molecules in...
Microglia play important roles in maintaining brain homeostasis and neurodegeneration. The discovery of genetic variants in genes predominately or exclusively expressed in myeloid cells, such as Apolipoprotein E (APOE) and triggering receptor expressed o
Differential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain The pharmacological attenuation of glial activation represents a novel approach for controlling neuropathic pain, but the role of microglial and astroglial... J Mika,M Osikowicz,E Rojewska...
Constitution of different types of neurons in different nuclei or areas of the central nervous system (CNS), such as the cerebral cortical layers I–VI, is a well-known neurobiological phenomenon and has been enlightened by recently advanced high cell-resolution technologies [1,2]. Glial cells,...